The aim of this study was to assess whether modulated electro-hyperthermia (mEHT) can
induce an abscopal effect and thereby enhance the antitumor effects of immunotherapy. We …

The Omicron subvariants of SARS-CoV-2 have multiple mutations in the S-proteins and show
high transmissibility. We previously reported that tea catechin (−)-epigallocatechin gallate (…

Liposomally formulated indocyanine green (LP-ICG) has drawn much attention as a highly
sensitive near-infrared (NIR)-fluorescence probe for tumors or lymph nodes in vivo. We …

Mastermind (Mam) is one of the elements of Notch signaling, a system that plays a pivotal
role in metazoan development. Mam proteins form transcriptionally activating complexes with …

We have rationally designed and synthesized a novel near-infrared (NIR) photoactivating
probe, designated by iDOPE, in which an indocyanine green (ICG) fluorophore is covalently …

Polyamines play important roles in cell growth mainly through their interaction with RNA.
We have previously reported that polyamines stimulate the synthesis of oligopeptide-binding …

Glioblastoma (GBM) is the most common malignant brain tumor, and infiltrates into the
surrounding normal brain tissue. Induction of a tumor-specific immune response is one of the best …

A number of sperm proteins are involved in the processes from gamete adhesion to fusion,
but the underlying mechanism is still unclear. Here, we established a mouse mutant, the …

It is known that the level of protein-conjugated acrolein in plasma is a good marker of chronic
renal failure and brain infarction. Thus, studies were carried out to determine which kinds of …

Hepatitis A virus (HAV) infection is one of the major causes of acute hepatitis and acute liver
failure in developing and developed countries. Although effective vaccines for HAV infection …