Alongside cancer cells, tumours exhibit a complex stroma containing a repertoire of cells,
matrix molecules and soluble factors that actively crosstalk between each other. Recognition of …

Background Head and neck squamous cell carcinoma (HNSCC) carries poor survival
outcomes despite recent progress in cancer treatment in general. Angiogenesis is crucial for …

Background Despite the importance of immune checkpoints in immunotherapy, the prognostic
value of these molecules remains controversial in oral squamous cell carcinoma (OSCC). …

Objectives Immunotherapy and personalized medicine therapeutics are emerging as
promising approaches in the management of head and neck squamous cell carcinoma (HNSCC). …

IL‐17C and its receptor IL‐17RA/IL‐17RE identify human oral epithelial cell as an
inflammatory cell in recurrent aphthous ulcer - Al‐Samadi - 2014 - Journal of Oral Pathology & …

Colorectal cancer (CRC) is one of the most common cancers in both genders. Even though
interleukin (IL)-17A was shown to play an important role in intestinal tumourigenesis and …

Background Immune checkpoint inhibitors (ICIs), primarily anti-PD-1, are currently used to
treat patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC). …

Introduction: Oral tongue squamous cell carcinoma (OTSCC) is the most common cancer of
the oral cavity. Contradictory results have been observed on the involvement of herpes …

In vitro cancer drug testing carries a low predictive value. We developed the human
leiomyoma–derived matrix “Myogel” to better mimic the human tumor microenvironment (TME). We …

Objective Evidence of increased apoptosis is observed in periodontitis and may be associated
with destruction of the periodontal tissue caused by the increased cell death, with the …