[HTML][HTML] The evolving landscape of biomarker testing for non-small cell lung cancer in Europe
KM Kerr, F Bibeau, E Thunnissen, J Botling, A Ryška… - Lung Cancer, 2021 - Elsevier
The discovery of oncogenic driver mutations rendering non-small cell lung cancer (NSCLC)
targetable by small-molecule inhibitors, and the development of immunotherapies, have …
targetable by small-molecule inhibitors, and the development of immunotherapies, have …
[HTML][HTML] Testing for ROS1 in non-small cell lung cancer: a review with recommendations
L Bubendorf, R Büttner, F Al-Dayel, M Dietel… - Virchows Archiv, 2016 - Springer
Rearrangements of the ROS1 gene occur in 1–2 % of non-small cell lung cancers (NSCLCs).
Crizotinib, a highly effective inhibitor of ROS1 kinase activity, is now FDA-approved for the …
Crizotinib, a highly effective inhibitor of ROS1 kinase activity, is now FDA-approved for the …
[HTML][HTML] Future perspective for the application of predictive biomarker testing in advanced stage non-small cell lung cancer
VD de Jager, W Timens, A Bayle, J Botling… - The Lancet Regional …, 2024 - thelancet.com
For patients with advanced stage non-small cell lung cancer (NSCLC), treatment strategies
have changed significantly due to the introduction of targeted therapies and immunotherapy. …
have changed significantly due to the introduction of targeted therapies and immunotherapy. …
Mammary analogue secretory carcinoma of salivary glands, containing the ETV6-NTRK3 fusion gene: a hitherto undescribed salivary gland tumor entity
…, F Passador-Santos, A Ryska… - The American journal …, 2010 - journals.lww.com
We present a series of 16 salivary gland tumors with histomorphologic and
immunohistochemical features reminiscent of secretory carcinoma of the breast. This is a hitherto …
immunohistochemical features reminiscent of secretory carcinoma of the breast. This is a hitherto …
[HTML][HTML] Somatic mutations of CADM1 in aldosterone-producing adenomas and gap junction-dependent regulation of aldosterone production
…, PJ King, WM Drake, M Gurnell, J Ceral, A Ryska… - Nature …, 2023 - nature.com
Aldosterone-producing adenomas (APAs) are the commonest curable cause of hypertension.
Most have gain-of-function somatic mutations of ion channels or transporters. Herein we …
Most have gain-of-function somatic mutations of ion channels or transporters. Herein we …
[HTML][HTML] Prognostic value of stromal tumor-infiltrating lymphocytes in young, node-negative, triple-negative breast cancer patients who did not receive (neo) adjuvant …
…, A Sapino, E Chmielik, A Ryska… - Journal of Clinical …, 2022 - ncbi.nlm.nih.gov
PURPOSE Triple-negative breast cancer (TNBC) is considered aggressive, and therefore,
virtually all young patients with TNBC receive (neo) adjuvant chemotherapy. Increased …
virtually all young patients with TNBC receive (neo) adjuvant chemotherapy. Increased …
[HTML][HTML] Mature dendritic cells correlate with favorable immune infiltrate and improved prognosis in ovarian carcinoma patients
…, C Sautes-Fridman, WH Fridman, A Ryska… - … for immunotherapy of …, 2018 - Springer
A high density of tumor-infiltrating CD8 + T cells and CD20 + B cells correlates with prolonged
survival in patients with a wide variety of human cancers, including high-grade serous …
survival in patients with a wide variety of human cancers, including high-grade serous …
Tumor-infiltrating lymphocytes predict response to neoadjuvant chemotherapy in patients with breast carcinoma
H Hornychova, B Melichar, M Tomšová… - Cancer …, 2008 - Taylor & Francis
Tumor-infiltrating leukocytes and other immunohistochemical parameters were evaluated in
pretherapeutic biopsies and resection specimens in 73 patients undergoing neoadjuvant …
pretherapeutic biopsies and resection specimens in 73 patients undergoing neoadjuvant …
Somatic mutations in the RET proto-oncogene in sporadic medullary thyroid carcinomas
…, J Vcelak, Z Novak, J Duskova, A Ryska… - Molecular and cellular …, 2008 - Elsevier
The frequency and prognostic relevance of RET proto-oncogene somatic mutations in
sporadic medullary thyroid carcinoma (MTC) remain controversial. In order to study somatic …
sporadic medullary thyroid carcinoma (MTC) remain controversial. In order to study somatic …
An autologous dendritic cell vaccine promotes anticancer immunity in patients with ovarian cancer with low mutational burden and cold tumors
…, I Praznovec, MJ Halaska, L Rob, A Ryska… - Clinical Cancer …, 2022 - AACR
Purpose: The successful implementation of immune checkpoint inhibitors (ICI) in the clinical
management of various solid tumors has raised considerable expectations for patients with …
management of various solid tumors has raised considerable expectations for patients with …