Similar articles for PMID: 28551618

Year	Number of Results
2007	1
2008	4
2009	6
2010	4
2011	10
2012	4
2013	6
2014	7
2015	14
2016	14
2017	10
2018	14
2019	11
2020	6
2021	13
2022	12
2023	7
2024	0

1

MEK162 Enhances Antitumor Activity of 5-Fluorouracil and Trifluridine in KRAS-mutated Human Colorectal Cancer Cell Lines.

Gong J, Chen Y, Yang L, Pillai R, Shirasawa S, Fakih M. Gong J, et al. Anticancer Res. 2017 Jun;37(6):2831-2838. doi: 10.21873/anticanres.11634. Anticancer Res. 2017. PMID: 28551618 Free PMC article.

2

Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells.

Little AS, Balmanno K, Sale MJ, Newman S, Dry JR, Hampson M, Edwards PA, Smith PD, Cook SJ. Little AS, et al. Sci Signal. 2011 Mar 29;4(166):ra17. doi: 10.1126/scisignal.2001752. Sci Signal. 2011. PMID: 21447798 Corrected and republished.

3

KRAS/BRAF mutation status and ERK1/2 activation as biomarkers for MEK1/2 inhibitor therapy in colorectal cancer.

Yeh JJ, Routh ED, Rubinas T, Peacock J, Martin TD, Shen XJ, Sandler RS, Kim HJ, Keku TO, Der CJ. Yeh JJ, et al. Mol Cancer Ther. 2009 Apr;8(4):834-43. doi: 10.1158/1535-7163.MCT-08-0972. Mol Cancer Ther. 2009. PMID: 19372556 Free PMC article.

4

Chemotherapeutic effects of MEK kinase inhibitor and BRAF kinase inhibitor on KRAS-mutated human colon cancer cell lines with different microsatellite instability.

Kim KO, Park WJ, Jung Y, Lee WS. Kim KO, et al. J Chemother. 2020 Dec;32(8):437-444. doi: 10.1080/1120009X.2020.1829326. Epub 2020 Oct 14. J Chemother. 2020. PMID: 33052075

5

Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines.

Balmanno K, Chell SD, Gillings AS, Hayat S, Cook SJ. Balmanno K, et al. Int J Cancer. 2009 Nov 15;125(10):2332-41. doi: 10.1002/ijc.24604. Int J Cancer. 2009. PMID: 19637312 Free article.

6

Preclinical activity of the rational combination of selumetinib (AZD6244) in combination with vorinostat in KRAS-mutant colorectal cancer models.

Morelli MP, Tentler JJ, Kulikowski GN, Tan AC, Bradshaw-Pierce EL, Pitts TM, Brown AM, Nallapareddy S, Arcaroli JJ, Serkova NJ, Hidalgo M, Ciardiello F, Eckhardt SG. Morelli MP, et al. Clin Cancer Res. 2012 Feb 15;18(4):1051-62. doi: 10.1158/1078-0432.CCR-11-1507. Epub 2011 Dec 15. Clin Cancer Res. 2012. PMID: 22173548 Free PMC article.

7

Effect of simvastatin on cetuximab resistance in human colorectal cancer with KRAS mutations.

Lee J, Lee I, Han B, Park JO, Jang J, Park C, Kang WK. Lee J, et al. J Natl Cancer Inst. 2011 Apr 20;103(8):674-88. doi: 10.1093/jnci/djr070. Epub 2011 Mar 11. J Natl Cancer Inst. 2011. PMID: 21398618

8

Dasatinib sensitizes KRAS mutant colorectal tumors to cetuximab.

Dunn EF, Iida M, Myers RA, Campbell DA, Hintz KA, Armstrong EA, Li C, Wheeler DL. Dunn EF, et al. Oncogene. 2011 Feb 3;30(5):561-74. doi: 10.1038/onc.2010.430. Epub 2010 Oct 18. Oncogene. 2011. PMID: 20956938 Free PMC article.

9

A phase I study of selumetinib (AZD6244/ARRY-142866), a MEK1/2 inhibitor, in combination with cetuximab in refractory solid tumors and KRAS mutant colorectal cancer.

Deming DA, Cavalcante LL, Lubner SJ, Mulkerin DL, LoConte NK, Eickhoff JC, Kolesar JM, Fioravanti S, Greten TF, Compton K, Doyle AG, Wilding G, Duffy A, Liu G. Deming DA, et al. Invest New Drugs. 2016 Apr;34(2):168-75. doi: 10.1007/s10637-015-0314-7. Epub 2015 Dec 14. Invest New Drugs. 2016. PMID: 26666244 Free PMC article. Clinical Trial.

10

Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K and RPS6 activation.

Grasso S, Tristante E, Saceda M, Carbonell P, Mayor-López L, Carballo-Santana M, Carrasco-García E, Rocamora-Reverte L, García-Morales P, Carballo F, Ferragut JA, Martínez-Lacaci I. Grasso S, et al. Neoplasia. 2014 Oct 23;16(10):845-60. doi: 10.1016/j.neo.2014.08.011. eCollection 2014 Oct. Neoplasia. 2014. PMID: 25379021 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Results by year

Text availability

Article attribute

Article type

Publication date

124 results

Results by year