Endoprosthetic treatment of metastatic pathological fractures

Anticancer Res. 1998 May-Jun;18(3C):2251-2.

Abstract

Due to a prolonged time of survival patients with lowrisk skeletal dissemination may develop a local relapse after surgical treatment of a pathological fracture. In a series of 180 patients with bone metastases of breast cancer, a local metastatic recurrency was observed 8-36 months after operative treatment in 12 patients. All of them had a receptor-positive primary and were free from visceral metastases; only one had received radiotherapy postoperatively. Patients with low-risk disease therefore should undergo more radial surgical procedures than patients with poor prognosis, in whom reconstitution of stability represents the most important therapeutic goal. In cases with low-risk disease and histologically proven residual tumour a postoperative irradiation should be administered as a rule.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Bone Cements
  • Bone Neoplasms / complications*
  • Bone Neoplasms / secondary*
  • Bone Neoplasms / surgery
  • Breast Neoplasms / pathology*
  • Female
  • Fractures, Spontaneous / surgery*
  • Humans
  • Middle Aged
  • Prosthesis Implantation
  • Risk Factors

Substances

  • Bone Cements