Abstract
We present a case of primary non-Hodgkin's lymphoma of the uterine cervix, Ann Arbor stage IE. This 64-year-old multiparous Japanese woman showed markedly elevated serum levels of lactate dehydrogenase (LDH) and of soluble interleukin-2 receptor (sIL-2R) at the time of diagnosis. Combination chemotherapy was administered and consisted of pirarubicin, cyclophosphamide, vincristine sulfate, and prednisolone (THP-COP). After 3 courses of such therapy, the serum levels of LDH and of sIL-2R decreased within normal limits, and the patient achieved a complete remission.
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Cervix Uteri / pathology
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Cyclophosphamide / administration & dosage
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Doxorubicin / administration & dosage
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Doxorubicin / analogs & derivatives
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Female
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Humans
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Immunohistochemistry
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L-Lactate Dehydrogenase / blood
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Lymphoma, Large B-Cell, Diffuse / diagnosis
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Lymphoma, Large B-Cell, Diffuse / drug therapy*
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Lymphoma, Large B-Cell, Diffuse / pathology
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Magnetic Resonance Imaging
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Middle Aged
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Neoplasm Staging
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Prednisolone / administration & dosage
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Receptors, Interleukin-2 / blood
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Remission Induction
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Uterine Cervical Neoplasms / diagnosis
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Uterine Cervical Neoplasms / drug therapy*
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Uterine Cervical Neoplasms / pathology
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Vincristine / administration & dosage
Substances
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Receptors, Interleukin-2
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Vincristine
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Doxorubicin
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Cyclophosphamide
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Prednisolone
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L-Lactate Dehydrogenase