Isolation and nucleotide sequence of a cloned cardionatrin cDNA

B P Kennedy; J J Marsden; T G Flynn; A J de Bold; P L Davies

doi:10.1016/0006-291x(84)91201-4

Isolation and nucleotide sequence of a cloned cardionatrin cDNA

Biochem Biophys Res Commun. 1984 Aug 16;122(3):1076-82. doi: 10.1016/0006-291x(84)91201-4.

Authors

B P Kennedy, J J Marsden, T G Flynn, A J de Bold, P L Davies

PMID: 6236804
DOI: 10.1016/0006-291x(84)91201-4

Abstract

A cloned cDNA which codes for the C-terminal 62 residues of the precursor molecule for the atrial natriuretic factor, cardionatrin, has been isolated and sequenced. The nucleotide sequence confirms the amino acid sequence of cardionatrin 1-28 previously determined, and positions this peptide at the C-terminal end of the precursor just two residues away from the termination codon.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Animals
Atrial Natriuretic Factor
Base Sequence
Cloning, Molecular*
DNA / isolation & purification*
Heart Atria / metabolism
Heart Ventricles / metabolism
Male
Muscle Proteins / genetics*
Myocardium / metabolism
Nucleic Acid Hybridization
Rats
Rats, Inbred Strains

Substances

Muscle Proteins
Atrial Natriuretic Factor
DNA

Associated data

GENBANK/K02062
GENBANK/K02063