Utilization of radiotherapy and stereotactic body radiation therapy for renal cell cancer in the USA

Future Oncol. 2018 Apr;14(9):819-827. doi: 10.2217/fon-2017-0536. Epub 2018 Mar 12.

Abstract

Aim: This study evaluated national practice patterns of cT1N0M0 renal cell cancer, with a focus on stereotactic body radiation therapy (SBRT) utilization.

Methods: The National Cancer Database was queried (2004-2013) for patients with newly-diagnosed cT1a/bN0M0 renal cell cancer that received definitive treatment. Temporal trends in utilization were tabulated.

Results: Altogether, 138,495 patients met inclusion criteria; 13,725 (9.9%) patients received ablative therapy, 57,924 (41.8%) partial nephrectomy, 67,168 (48.5%) radical nephrectomy and 308 (0.2%) external beam radiation therapy (EBRT). The proportion of EBRT that was SBRT increased substantially from 25% in 2004 to 95.4% in 2013, with a sharp inflection point from 2005 to 2006.

Conclusion: SBRT utilization has sharply risen over time; in most recent years, the vast majority of EBRT is delivered in the form of SBRT.

Keywords: kidney cancer; nephrectomy; radiation therapy; renal cell carcinoma; stereotactic ablative radiation therapy; stereotactic body radiation therapy.

MeSH terms

  • Carcinoma, Renal Cell / epidemiology
  • Carcinoma, Renal Cell / pathology
  • Carcinoma, Renal Cell / radiotherapy*
  • Carcinoma, Renal Cell / surgery*
  • Humans
  • Nephrectomy
  • Radiosurgery*
  • United States / epidemiology