Nesfatin-1: a new energy-regulating peptide with pleiotropic functions. Implications at cardiovascular level

Endocrine. 2016 Apr;52(1):11-29. doi: 10.1007/s12020-015-0819-z. Epub 2015 Dec 12.

Abstract

Nesfatin-1 is a new energy-regulating peptide widely expressed at both central and peripheral tissues with pleiotropic effects. In the last years, the study of nesfatin-1 actions and its possible implication in the development of different diseases has created a great interest among the scientific community. In this review, we will summarize nesfatin-1 main functions, focusing on its cardiovascular implications.

Keywords: Cardiovascular; Energy homeostasis; Metabolism; Nesfatin-1; Viability.

Publication types

  • Review

MeSH terms

  • Adipose Tissue / metabolism
  • Animals
  • Calcium-Binding Proteins / genetics*
  • Calcium-Binding Proteins / physiology*
  • Cardiovascular Physiological Phenomena / genetics*
  • DNA-Binding Proteins / genetics*
  • DNA-Binding Proteins / physiology*
  • Energy Metabolism / genetics*
  • Energy Metabolism / physiology*
  • Humans
  • Nerve Tissue Proteins / genetics*
  • Nerve Tissue Proteins / physiology*
  • Nucleobindins

Substances

  • Calcium-Binding Proteins
  • DNA-Binding Proteins
  • NUCB2 protein, human
  • Nerve Tissue Proteins
  • Nucleobindins