Quantification of crypt and stem cell evolution in the normal and neoplastic human colon

Affiliations

• ¹ Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.
• ² Cavendish Laboratory, Department of Physics, J.J. Thomson Avenue, University of Cambridge, Cambridge CB3 0HE, UK.
• ³ Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford OX2 6GG, UK.
• ⁴ Department of Histopathology, University College London, London WC1E 6BT, UK.
• ⁵ Cellular Pathology, Northwest London Hospitals NHS Trust, London HA1 3UJ, UK.
• ⁶ St. Mark's Hospital, Watford Road, Harrow HA1 3UJ, UK.
• ⁷ Cavendish Laboratory, Department of Physics, J.J. Thomson Avenue, University of Cambridge, Cambridge CB3 0HE, UK; The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK; The Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK.
• ⁸ Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK; Department of Pathology, Academic Medical Centre, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands.
• ⁹ Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK; Center for Evolution and Cancer, 2340 Sutter Street, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: t.graham@qmul.ac.uk.