Gastric cancer and trastuzumab: first biologic therapy in gastric cancer

Ther Adv Med Oncol. 2013 Mar;5(2):143-51. doi: 10.1177/1758834012469429.

Abstract

Gastric cancer remains difficult to cure and has a poor overall prognosis. Chemotherapy and multimodality therapy has shown some benefit in the treatment of gastric cancer. Current therapies for gastric cancer have their limitations; thus, we are in need of newer treatment options including targeted therapies. Here, we review the biologic therapy with trastuzumab in human epidermal growth factor receptor 2 (HER2)+ gastric cancer.

Keywords: gastric cancer; trastuzumab.