Continence, potency and oncological outcomes after robotic-assisted radical prostatectomy: early trifecta results of a high-volume surgeon

BJU Int. 2010 Sep;106(5):696-702. doi: 10.1111/j.1464-410X.2010.09541.x. Epub 2010 Aug 12.

Abstract

Objective: • To evaluate early trifecta outcomes after robotic-assisted radical prostatectomy (RARP) performed by a high-volume surgeon.

Patients and methods: • We evaluated prospectively 1100 consecutive patients who underwent RARP performed by one surgeon. In all, 541 men were considered potent before RARP; of these 404 underwent bilateral full nerve sparing and were included in this analysis. • Baseline and postoperative urinary and sexual functions were assessed using self-administered validated questionnaires. • Postoperative continence was defined as the use of no pads; potency was defined as the ability to achieve and maintain satisfactory erections for sexual intercourse >50% of times, with or without the use of oral phosphodiesterase type 5 inhibitors; Biochemical recurrence (BCR) was defined as two consecutive PSA levels of >0.2 ng/mL after RARP. • Results were compared between three age groups: Group 1, ≤ 55 years, Group 2, 56-65 years and Group 3, >65 years.

Results: • The trifecta rates at 6 weeks, 3, 6, 12, and 18 months after RARP were 42.8%, 65.3%, 80.3%, 86% and 91%, respectively. • There were no statistically significant differences in the continence and BCR-free rates between the three age groups at all postoperative intervals analysed. • Nevertheless, younger men had higher potency rates and shorter time to recovery of sexual function when compared with older men at 6 weeks, 3, 6 and 12 months after RARP (P < 0.01 at all time points). • Similarly, younger men had higher trifecta rates at 6 weeks, 3 and 6 months after RARP compared with older men (P < 0.01 at all time points).

Conclusion: • RARP offers excellent short-term trifecta outcomes when performed by an experienced surgeon. • Younger men had higher overall trifecta rates when compared with older men at 6 weeks, 3 and 6 months after RARP.

Publication types

  • Evaluation Study

MeSH terms

  • Aged
  • Clinical Competence
  • Epidemiologic Methods
  • Erectile Dysfunction / etiology*
  • Erectile Dysfunction / rehabilitation
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Phosphodiesterase 5 Inhibitors / therapeutic use
  • Prostate-Specific Antigen / metabolism
  • Prostatectomy / adverse effects
  • Prostatectomy / methods*
  • Prostatic Neoplasms / rehabilitation*
  • Prostatic Neoplasms / surgery
  • Robotics*
  • Treatment Outcome
  • Urinary Incontinence / etiology*
  • Urinary Incontinence / rehabilitation

Substances

  • Phosphodiesterase 5 Inhibitors
  • Prostate-Specific Antigen