Erectile dysfunction after radiotherapy for prostate cancer

Am J Clin Oncol. 2009 Aug;32(4):443-7. doi: 10.1097/COC.0b013e318173a563.

Abstract

Erectile Dysfunction (ED) is a relatively common complication after radiotherapy for prostate cancer. The etiology of ED is unclear. It is likely related to age, pretreatment erectile function, androgen deprivation therapy, and the volume of tissue irradiated. It is unclear whether the dose to various parts of the penis, such as the penile bulb and corpora cavernosa, is related to the development of ED. Following radiotherapy, the early use of phosphodiesterase inhibitors probably reduces the risk of ED.

Publication types

  • Comparative Study
  • Meta-Analysis
  • Review

MeSH terms

  • Age Distribution
  • Aged
  • Dose-Response Relationship, Radiation
  • Erectile Dysfunction / epidemiology
  • Erectile Dysfunction / etiology*
  • Erectile Dysfunction / physiopathology
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Prognosis
  • Prostatectomy / adverse effects
  • Prostatectomy / methods
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / radiotherapy*
  • Prostatic Neoplasms / surgery
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted / adverse effects*
  • Radiotherapy Planning, Computer-Assisted / methods
  • Randomized Controlled Trials as Topic
  • Severity of Illness Index