Overview of the Disease Process IncidencePrognosisCurrent General Therapy Standards SurgeryAdjuvant RadiotherapyAdjuvant ChemotherapyAdjuvant Chemotherapy After D2 DissectionCombined ChemoradiotherapyAccomplishments During the Year TherapyWhat Needs To Be Done (Application of the Accomplishments) Controversies and DisagreementsFuture Directions Comments on Research CRITICS StudyCALGB 80101Obstacles to Progress.