Patterns of oral manifestation of HIV/AIDS among 225 Nigerian patients

Oral Dis. 2008 May;14(4):341-6. doi: 10.1111/j.1601-0825.2007.01384.x.

Abstract

Objective: The purpose of this study was to determine the prevalence of the oral manifestations of HIV/AIDS and to correlate the prevalence of these lesions with the stages of the disease in the Ife-Ijesa zone, Nigeria. No comprehensive data were available for correlating it with the staging of HIV/AIDS in this region.

Subjects: The pattern of oral HIV lesions as classified by the EC-Clearinghouse was studied in 225 confirmed consecutive HIV-infected patients in this zone.

Methods: Clinical dental examinations were conducted under natural daylight on all consenting HIV patients, sitting in an upright chair, using dental mirrors and probes.

Results: The prevalence of oral HIV lesions was 84.0%, with lesions ranging in number from one to six. The commonest HIV lesion was pseudo-membranous candidiasis (43.1%) followed by erythematous candidiasis (28.9%), angular cheilitis (28.9%), linear gingival erythema (24.0%) and ulcerations (8.9%). Lesions less commonly found were oral hairy leukoplakia (1.3%) and salivary gland swellings (1.3%). Heterosexual intercourse was the most common mode of transmission (94.7%) and HIV-1 (96.9%) the most prevalent pathogen among the study population. The majority of the patients were in the WHO clinical stage III (59.1%) and presented late.

Conclusions: The prevalence of oral HIV lesions in the present study was high.

MeSH terms

  • Adolescent
  • Adult
  • Candidiasis, Oral / complications
  • Cheilitis / complications
  • Erythema / complications
  • Female
  • HIV Infections / complications*
  • HIV Infections / pathology
  • HIV Infections / transmission
  • HIV Infections / virology
  • HIV-1 / isolation & purification
  • Heterosexuality
  • Humans
  • Leukoplakia, Hairy / complications
  • Male
  • Mouth Diseases / complications*
  • Nigeria
  • Oral Ulcer / complications
  • Prospective Studies