Successful pregnancy in stage IE primary non-Hodgkin's lymphoma of uterine cervix treated with neoadjuvant chemotherapy and conservative surgery

Oncology. 2007;72(3-4):261-4. doi: 10.1159/000113018. Epub 2008 Jan 10.

Abstract

Background: Primary non-Hodgkin's lymphoma involving the uterine cervix is extremely rare with a frequency of 0.008% of all cervical tumors. No standard treatment has been defined for this disease.

Case: A 29-year-old Caucasian woman with primary non-Hodgkin stage IE lymphoma of the uterine cervix was treated with neoadjuvant chemotherapy and conservative surgery. Three years after completion of primary treatment, she became pregnant and successfully delivered a full-term healthy baby.

Conclusion: This case report supports the data that a conservative strategy consisting of neoadjuvant chemotherapy followed by a uterine-preserving approach represents an adequate option for young highly motivated patients who desire to preserve the childbearing potential.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
  • Cyclophosphamide / administration & dosage
  • Doxorubicin / administration & dosage
  • Female
  • Humans
  • Lymphoma, Non-Hodgkin / drug therapy*
  • Lymphoma, Non-Hodgkin / surgery*
  • Neoadjuvant Therapy
  • Prednisone / administration & dosage
  • Pregnancy
  • Uterine Cervical Neoplasms / drug therapy*
  • Uterine Cervical Neoplasms / surgery*
  • Vincristine / administration & dosage

Substances

  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Prednisone

Supplementary concepts

  • CHOP protocol