Triple synchronous primary cervical, endometrial and ovarian cancer with four different histologic patterns

Arch Gynecol Obstet. 2007 Dec;276(6):655-8. doi: 10.1007/s00404-007-0392-7. Epub 2007 May 31.

Abstract

Background: Double synchronous primary cancers of gynecological cancers is a common event. However, triple synchronous primary gynecological cancers is an extremely rare event.

Case: A 50-year-old woman, para 0-0-0-0 was admitted to the hospital with a complaint of menorrhagia for 2 months. The preoperative evaluation and diagnosis was myoma uteri with bilateral ovarian tumor. Subtotal hysterectomy with bilateral salpingo-oophorectomy, and omentectomy were performed. The postoperative and pathologic findings were adenosquamous carcinoma of the endocervix, adenocarcinoma of the endometrium, low malignant potential of the right ovary and mucinous cystadenocarcinoma of the left ovary. She received a complete course of whole pelvic radiation. Unfortunately, she died from pulmonary embolism.

Conclusion: The occurrence of triple synchronous gynecological cancers is a rare and unique event deserving further studies.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / pathology
  • Adenofibroma / pathology
  • Carcinoma, Adenosquamous / pathology
  • Cystadenoma, Mucinous / pathology
  • Endometrial Neoplasms / pathology*
  • Female
  • Humans
  • Middle Aged
  • Neoplasms, Multiple Primary / pathology*
  • Ovarian Neoplasms / pathology*
  • Uterine Cervical Neoplasms / pathology*