Spontaneous regression of optic glioma in a patient with neurofibromatosis

Neurology. 1992 Mar;42(3 Pt 1):679-81. doi: 10.1212/wnl.42.3.679.

Abstract

We describe a young girl with neurofibromatosis and enlargement of the optic chiasm and intracranial left optic nerve. Serial MRIs over 32 months demonstrated spontaneous, marked reduction in the size of these lesions. Spontaneous regression must be considered in evaluating therapies for optic glioma.

Publication types

  • Case Reports

MeSH terms

  • Cranial Nerve Neoplasms / complications
  • Cranial Nerve Neoplasms / diagnosis*
  • Cranial Nerve Neoplasms / therapy
  • Female
  • Glioma / complications
  • Glioma / diagnosis*
  • Glioma / therapy
  • Humans
  • Infant
  • Magnetic Resonance Imaging
  • Neurofibromatosis 1 / complications
  • Neurofibromatosis 1 / diagnosis*
  • Neurofibromatosis 1 / therapy