Therapeutics targeting the innate immune system

Nat Rev Immunol. 2004 Jul;4(7):512-20. doi: 10.1038/nri1396.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adaptor Proteins, Signal Transducing*
  • Animals
  • Antigens, Differentiation / physiology
  • Asthma / immunology
  • Asthma / therapy
  • Carrier Proteins / physiology
  • Humans
  • Immune System / drug effects*
  • Immune System / physiology
  • Immunity, Innate* / drug effects
  • Immunotherapy
  • Infections / immunology
  • Infections / therapy
  • Intracellular Signaling Peptides and Proteins*
  • Ligands
  • Membrane Glycoproteins / classification
  • Membrane Glycoproteins / genetics
  • Membrane Glycoproteins / physiology
  • Mice
  • Models, Immunological
  • Multigene Family
  • Myeloid Differentiation Factor 88
  • NF-kappa B / physiology
  • Nod1 Signaling Adaptor Protein
  • Nod2 Signaling Adaptor Protein
  • Oligodeoxyribonucleotides / therapeutic use*
  • Receptors, Cell Surface / classification
  • Receptors, Cell Surface / genetics
  • Receptors, Cell Surface / physiology
  • Receptors, Immunologic / physiology
  • Signal Transduction
  • Toll-Like Receptors

Substances

  • Adaptor Proteins, Signal Transducing
  • Antigens, Differentiation
  • CPG-oligonucleotide
  • Carrier Proteins
  • Intracellular Signaling Peptides and Proteins
  • Ligands
  • MYD88 protein, human
  • Membrane Glycoproteins
  • Myd88 protein, mouse
  • Myeloid Differentiation Factor 88
  • NF-kappa B
  • NOD1 protein, human
  • NOD2 protein, human
  • Nod1 Signaling Adaptor Protein
  • Nod2 Signaling Adaptor Protein
  • Oligodeoxyribonucleotides
  • Receptors, Cell Surface
  • Receptors, Immunologic
  • Toll-Like Receptors