The relationship between hypoalbuminaemia, tumour volume and the systemic inflammatory response in patients with colorectal liver metastases

Br J Cancer. 2004 Jul 19;91(2):205-7. doi: 10.1038/sj.bjc.6601886.

Abstract

The relationship between hypoalbuminaemia, tumour volume and C-reactive protein was examined in patients with colorectal liver metastases (n=57). On multiple regression analysis, albumin concentrations were independently associated with C-reactive protein (r=0.56, P<0.001) but not percentage hepatic replacement (P=0.34). These results show that hypoalbuminaemia is associated with the presence of a systemic inflammatory response rather than tumour volume in patients with colorectal liver metastases.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alanine Transaminase / blood
  • Alkaline Phosphatase / blood
  • Aspartate Aminotransferases / blood
  • C-Reactive Protein / analysis
  • Colorectal Neoplasms / enzymology
  • Colorectal Neoplasms / pathology*
  • Female
  • Humans
  • Hypoalbuminemia / etiology*
  • Inflammation / etiology
  • Liver Function Tests
  • Liver Neoplasms / enzymology
  • Liver Neoplasms / secondary*
  • Male
  • Middle Aged
  • Serum Albumin / analysis

Substances

  • Serum Albumin
  • C-Reactive Protein
  • Aspartate Aminotransferases
  • Alanine Transaminase
  • Alkaline Phosphatase