Abstract
Laser immunotherapy is a novel approach for the treatment of metastatic tumors. It combines a selective photothermal laser-tissue interaction for direct tumor destruction and an immunoadjuvant-directed simulation for immune responses. In experiments using a rat metastatic tumor model, laser immunotherapy resulted in the eradication of both treated primary tumors and untreated metastases at remote sites. It also induced anti-tumor resistance.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Cell Line, Tumor
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Chitin / analogs & derivatives*
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Chitin / chemical synthesis
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Chitin / pharmacology
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Chitin / therapeutic use
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Chitosan*
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Female
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Immunotherapy / methods*
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Indocyanine Green / pharmacology
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Injections, Intralesional
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Injections, Subcutaneous
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Laser Therapy*
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Mammary Neoplasms, Experimental / mortality
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Mammary Neoplasms, Experimental / pathology
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Mammary Neoplasms, Experimental / therapy*
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Neoplasm Metastasis / therapy*
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Neoplasm Transplantation
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Rats
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Survival Analysis
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Survival Rate
Substances
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glycated chitosan
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Chitin
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Chitosan
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Indocyanine Green