Somatostatin receptor scintigraphy for bronchial carcinoid follow-up

Clin Nucl Med. 2003 Jul;28(7):548-52. doi: 10.1097/00003072-200307000-00003.

Abstract

Purpose: Somatostatin receptor scintigraphy (SRS) has been used to diagnose bronchial carcinoids (BC) and is a valuable tool for accurate staging of BC. The aim of this study was to evaluate the role of SRS in restaging BC and following patients after treatment.

Methods: Thirty-one patients (18 male, 13 female) with confirmed BC who were referred during the last 7 years were included. Patients were examined via chest radiograph (12 studies), chest or abdominal computed tomography (CT; 28 scans), chest magnetic resonance imaging (2 scans), and liver ultrasound (5 scans).

Results: Overall, in 22 patients (71%), SRS confirmed the data obtained by other diagnostic procedures (16 negative and 6 positive findings). In 6 patients, SRS showed focal lesions not previously demonstrated. In 2 patients, SRS resolved uncertain findings of CT. In 1 patient, SRS showed fewer lesions compared with CT. In 8 of 31 patients, important diagnostic information obtained by SRS was not revealed by any other imaging procedure.

Conclusion: Our results indicate that SRS is a reliable, noninvasive method that could be considered the principal follow-up procedure in patients with BC.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Bronchial Neoplasms / diagnosis
  • Bronchial Neoplasms / diagnostic imaging*
  • Bronchial Neoplasms / metabolism*
  • Bronchial Neoplasms / surgery
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Staging / methods
  • Octreotide / analogs & derivatives*
  • Octreotide / pharmacokinetics*
  • Pentetic Acid / analogs & derivatives*
  • Pentetic Acid / pharmacokinetics*
  • Radionuclide Imaging
  • Radiopharmaceuticals / pharmacokinetics
  • Receptors, Somatostatin / metabolism*
  • Reproducibility of Results
  • Sensitivity and Specificity

Substances

  • Radiopharmaceuticals
  • Receptors, Somatostatin
  • SDZ 215-811
  • Pentetic Acid
  • Octreotide