PIP: During 1986-1987, 192 women aged 26-86 with invasive breast cancer were treated with radiotherapy, hormonotherapy, and chemotherapy and then underwent modified radical mastectomy or wide local excision at Luis Castelazo Ayala Hospital of Obstetrics and Gynecology of the Mexican Social Security Institute in Mexico City. At diagnosis, metastatic bone surveys and bone scans showed that no one had distant metastasis. The physicians used incisional biopsy to determine the type of breast carcinoma (infiltrating ductal carcinoma [IDC] and infiltrating lobular carcinoma [ILC]). The researchers aimed to identify prognostic factors in primary breast cancer. 156 patients (81.3%) and 36 patients (18.7%) had IDC and ILC, respectively. Among women with IDC, axillary nodes were involved in 23.5% of premenopausal women and in 23% of postmenopausal women. 83.8% of all patients with IDC and 52.3% of IDC patients aged at least 50 had clinical stage III disease. Among women with ILC, axillary nodes were involved in 19.4% of premenopausal women and in 19.4% of postmenopausal women. 70% of all patients with ILC and 84.6% of ILC patients aged at least 50 had clinical stage III disease. All the patients had advanced breast cancer (i.e., clinical stage II and III). Some tumors were only estrogen receptor types, while others were only progesterone receptor types. Some tumors were even both receptor types, while another category had neither steroid hormone receptor. Survival rates for metastatic and non-metastatic breast cancer was greater among postmenopausal women than premenopausal women (32.7% vs. 14.8% and 21.8% vs. 12.8% for ICD and 19.4% vs. 8.4% and 30.5% vs. 13.9% for ILC, respectively). These findings suggest that axillary node status, status of estrogen and progesterone receptors, and menstrual status were important prognostic factors of breast cancer.