Lymphoepithelioma-like carcinoma of the breast

APMIS. 2002 Jun;110(6):447-50. doi: 10.1034/j.1600-0463.2002.100602.x.

Abstract

Lymphoepithelioma-like carcinoma (LELC) of the breast is a rare, newly recognized subtype of breast carcinoma. Distinction from medullary carcinoma is important because of the difference in biologic behavior of these two neoplasms and LELC of the breast is regarded as an unusual form of lobular carcinoma. We present the case of a 56-year-old female with a breast mass measuring 2 cm in diameter, which was diagnosed as invasive lobular carcinoma with LELC pattern. This is the ninth case reported in the English literature and to the best of our knowledge the first one with lymph node metastasis.

Publication types

  • Case Reports

MeSH terms

  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / pathology
  • Carcinoma, Lobular / diagnosis*
  • Carcinoma, Lobular / pathology
  • Carcinoma, Squamous Cell / diagnosis*
  • Carcinoma, Squamous Cell / pathology
  • Diagnosis, Differential
  • E2F6 Transcription Factor
  • Eosine Yellowish-(YS)
  • Epithelial Cells / metabolism
  • Female
  • Hematoxylin
  • Humans
  • Immunohistochemistry
  • Lymphatic Metastasis
  • Middle Aged
  • Repressor Proteins / analysis
  • Transcription Factors / analysis

Substances

  • E2F6 Transcription Factor
  • E2F6 protein, human
  • Repressor Proteins
  • Transcription Factors
  • Eosine Yellowish-(YS)
  • Hematoxylin