Abstract
We report herein a unique case of an esophageal collision tumor composed of a papillary adenocarcinoma and a large cell neuroendocrine carcinoma arising in a Barrett esophagus. Hematoxylin-eosin and silver staining patterns, immunohistochemistry, and electron microscopy of the large cell neuroendocrine component are discussed.
MeSH terms
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Adenocarcinoma, Papillary / chemistry
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Adenocarcinoma, Papillary / pathology*
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Adenocarcinoma, Papillary / surgery
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Barrett Esophagus / metabolism
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Barrett Esophagus / pathology*
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Barrett Esophagus / surgery
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Biomarkers, Tumor / analysis
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Carcinoma, Neuroendocrine / chemistry
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Carcinoma, Neuroendocrine / pathology*
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Carcinoma, Neuroendocrine / surgery
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Esophageal Neoplasms / chemistry
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Esophageal Neoplasms / pathology*
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Esophageal Neoplasms / surgery
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Humans
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Immunoenzyme Techniques
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Male
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Middle Aged
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Neoplasm Proteins / analysis
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Neoplasms, Second Primary / chemistry
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Neoplasms, Second Primary / pathology*
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Neoplasms, Second Primary / surgery
Substances
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Biomarkers, Tumor
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Neoplasm Proteins