Primary hormonal treatment for early endometrial carcinoma

Eur J Gynaecol Oncol. 1998;19(6):565-8.

Abstract

Four cases of clinical Stage I endometrial carcinoma initially treated with hormonal therapy are included in this study. Three of them resulted in tumor regression and two of them permitted a subsequent three pregnancies. All patients are alive and without evidence of disease with a median follow-up of 35.7 months (range 17 to 72 months). We believe this is a promising approach through which we may be able to offer a conservative treatment maintaining high survival rates and preserving childbearing potential. Diagnostic and therapeutic data for fertility-desiring patients with endometrial carcinoma are analyzed in this study.

Publication types

  • Clinical Trial

MeSH terms

  • Adenocarcinoma / drug therapy*
  • Adenocarcinoma / pathology
  • Adult
  • Antineoplastic Agents, Hormonal / therapeutic use*
  • Biopsy, Needle
  • Endometrial Neoplasms / drug therapy*
  • Endometrial Neoplasms / pathology
  • Female
  • Follow-Up Studies
  • Humans
  • Medroxyprogesterone Acetate / therapeutic use*
  • Neoplasm Staging
  • Treatment Outcome

Substances

  • Antineoplastic Agents, Hormonal
  • Medroxyprogesterone Acetate