Management of metastatic urothelial cancer: the role of surgery as an adjunct to chemotherapy

Authors

  • Robert S. Svatek The University of Texas MD Anderson Cancer Center, Department of Urologic Oncology, Houston, TX
  • Arlene Siefker-Radtke The University of Texas MD Anderson Cancer Center, Department of Genitourinary Medical Oncology, Houston, TX
  • Colin P. Dinney The University of Texas MD Anderson Cancer Center, Department of Urologic Oncology, Houston, TX

DOI:

https://doi.org/10.5489/cuaj.1203

Abstract

Metastatic or unresectable disease is identified in approximately
20% of patients presenting with invasive urothelial cancer. In
addition, up to 50% of patients will develop metastases following
radical cystectomy for clinically localized disease. Multiagent
cisplatin-based chemotherapy is considered standard first-line
treatment for these patients. Although urothelial cancer is considered
a chemosensitive tumour, metastatic disease is associated
with poor prognosis and short-term survival. Here, we review the
role of a multidisciplinary approach to treating patients with metastatic
urothelial cancer.

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Author Biographies

Robert S. Svatek, The University of Texas MD Anderson Cancer Center, Department of Urologic Oncology, Houston, TX

Arlene Siefker-Radtke, The University of Texas MD Anderson Cancer Center, Department of Genitourinary Medical Oncology, Houston, TX

Colin P. Dinney, The University of Texas MD Anderson Cancer Center, Department of Urologic Oncology, Houston, TX

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How to Cite

Svatek, R. S., Siefker-Radtke, A., & Dinney, C. P. (2013). Management of metastatic urothelial cancer: the role of surgery as an adjunct to chemotherapy. Canadian Urological Association Journal, 3(6-S4), S228-S231. https://doi.org/10.5489/cuaj.1203

Issue

Vol. 3 No. 6-S4 (2009): CUAJ December Suppl 4

Section

Review

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