Article Text
Summary
A 58-year-old female patient presented with several weeks history of significant bilateral knee pain. Initial knee radiographs demonstrated lucencies of the bony cortex while extensive osteolytic lesions on a routine chest radiograph were suggestive of multiple myeloma or bony metastases. Biochemical investigation revealed primary hyperparathyroidism with renal insufficiency. A parathyroid adenoma was demonstrated on a neck ultrasound and sestamibi scan and subsequently confirmed by histology. We illustrate a case of primary hyperparathyroidism with osteitis fibrosa cystica and brown tumours which were initially mistaken for malignant disease.
- Primary hyperparathyroidism
- Brown tumour
- Osteitis fibrosa cystica
- Parathyroid adenoma
- Scintigraphy
- Ultra sound
- X-ray
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Footnotes
Contributors LJ authored the case presentation, differential diagnosis, outcome/follow-up and learning points sections and coauthored the investigation and treatment sections with WH and SR. MJ authored the summary and background, and coauthored the discussion section with WH and SR. WH and SR provided supervision, analysis and interpretation of data, drafting, and editing and coauthored the investigation, treatment, and discussion sections.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.