Original ArticleNatural history of node-negative breast cancer: are conventional prognostic factors predictors of time to relapse?
References (39)
- et al.
Age as prognostic factor in premenopausal breast carcinoma
Lancet
(1993) - et al.
Does breast cancer exist in a state of chaos?
Eur J Cancer
(1999) - et al.
Angiogenesis and estrogen receptor in young women with breast cancer
Int Radiat Oncol Biol Phys
(1997) - et al.
Eight-year results of a prospective non-randomized study on therapy of small breast cancer. The German Breast Cancer Study Group (GBSG)
Eur J Cancer
(1998) - et al.
Fifth International Conference on Adjuvant Therapy of Breast Cancer, St Gallen, March 1995. International Consensus Panel on the Treatment of Primary Breast Cancer
Eur J Cancer
(1995) - et al.
Oestrogen receptors, sites of metastatic disease and survival in recurrent breast cancer
Eur J Cancer
(1981) - et al.
Relation of tumour size, lymph node status, and survival in 24,740 breast cancer cases
Cancer
(1989) - et al.
Factors influencing prognosis in node-negative breast carcinoma: analysis of 767 T1N0M0/T2N0M0 patients with long-term follow-up
J Clin Oncol
(1993) - et al.
Pathological prognostic factors in stage I (T1N0M0) and stage II (T1N1M0) breast carcinoma: a study of 644 patients with median follow-up of 18 years
J Clin Oncol
(1989) - et al.
Histological grading and prognostic in breast cancer: a study of 1409 cases of which 359 followed for 15 years
Br J Cancer
(1957)
Relative worth of estrogen or progesterone receptor and pathologic characteristics of differentiation as indicator of prognosis in node negative breast cancer patients: findings from National Surgical adjuvant Breast and Bowel Project Protocol B-06
J Clin Oncol
Age at first primary as a determinant of the incidence of bilateral breast cancer. Cumulative and relative risks in a population based case-control study
Cancer
The influence of young age on outcome in early stage breast cancer
Int J Radiat Oncol Biol Phys
Dormancy of mammary carcinoma after mastectomy
JNCI
Patterns of relapse and survival following radical mastectomy. Analysis of 716 consecutive patients
Cancer
Histologic malignancy grading of invasive ductal breast carcinoma. A regression analysis of prognostic factors in low-risk carcinomas from a multicenter trial
Cancer
Pathological correlates of survival in 378 lymph node-negative infiltrating ductal breast carcinomas. Mitotic count is the best single predictor
Cancer
Nuclear characteristics as indicators of prognosis in node negative breast cancer patients
Breast Cancer Res Treat
Node-negative breast cancer treated by modified radical mastectomy without adjuvant therapies: variables associated with disease recurrence and survivorship
J Clin Oncol
Cited by (20)
Metastasis-free interval in breast cancer patients: Thirty-year trends and time dependency of prognostic factors. A retrospective analysis based on a single institution experience
2018, BreastCitation Excerpt :Among all the variables characterizing node disease, only LNR appeared as a strong independent prognostic factor in our multivariate analysis [6]. Previous studies have already established that positive lymph nodes represent the most important prognostic factor of survival in breast cancer patients and that the worse outcome is directly correlated with the number of positive lymph nodes [30–32]. Even if the number of positive lymph nodes is significant, whenever LNR is also introduced in the model, it is only the LNR that appears as a strong independent prognostic factor [33].
Quantitative apparent diffusion coefficient measurement obtained by 3.0 Tesla MRI as a potential noninvasive marker of tumor aggressiveness in breast cancer
2016, European Journal of RadiologyCitation Excerpt :In LN negative patients, the presence of lymphovascular invasion (LVI) has been reported to adversely impact prognosis because patients with positive LVI had a higher rate of distant metastases, increased local recurrence rate after breast conservation therapy and a higher mortality rate [5,11]. Studies have also reported LVI as a possible independent prognostic factor [12,13]. However, due to limited sampling, preoperative assessment of LVI status of a tumor by core-biopsy is difficult.
Clinical data analysis using artificial neural networks (ANN) and principal component analysis (PCA) of patients with breast cancer after mastectomy
2007, Reports of Practical Oncology and RadiotherapyPrognostic value of lymphovascular invasion in women with lymph node negative invasive breast carcinoma
2006, European Journal of CancerMinimal and small size invasive breast cancer with no axillary lymph node involvement: The need for tailored adjuvant therapies
2004, Annals of OncologyCitation Excerpt :Controversy regarding the clinical algorithm for patients with small tumors is related to the limited information available on their prognosis [17]. Studies published reported a long-term DFS ranging between 79% and 98% [18–21]. Factors related to good prognosis were low grade [19, 20], old age [21, 22] and ER-negative disease [18, 21].
- f1
Address correspondence to: Dr Thierry Delozier, Service de Radiotherapie, Centre François Baclesse, Route de Lion/mer, B.P. 5026, F-14076 CAEN Cedex 5, France. Tel.: +33 231 45 50 50; Fax: +33 231 45 50 57; E-mail: [email protected]