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Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

Abstract

Of 10 distinct cloned DNA copies of mRNAs expressed in T lymphocytes but not in B lymphocytes and associated with membrane-bound polysomes, one hybridizes to a region of the genome that has rearranged in a T-cell lymphoma and several T-cell hybridomas. These characteristics suggest that it encodes one chain of the elusive antigen receptor on the surface of T lymphocytes.

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Hedrick, S., Cohen, D., Nielsen, E. et al. Isolation of cDNA clones encoding T cell-specific membrane-associated proteins. Nature 308, 149–153 (1984). https://doi.org/10.1038/308149a0

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