Original CommunicationPrognostic value of concomitant resection of extrahepatic disease in patients with liver metastases of colorectal origin
Section snippets
Methods and materials
Data were collected for 254 patients who had undergone hepatic resections with curative intent for the treatment of colorectal metastases in the Department of Surgery, Tokyo Metropolitan Bokutoh Hospital, from September 1988 to August 2005. The principal patient selection criteria were as follows: controlled primary disease, a macroscopic complete resection, and the preservation of an acceptable amount of liver parenchyma (40% of the total liver volume). In this study, a macroscopically
Characteristics of primary neoplasms
The primary neoplasm was located in the colon in 111 patients (59%) and in the rectum in 76 (41%). The degree of tumor differentiation was well differentiated in 92 patients (49%), moderately differentiated in 86 patients (46%), and poorly differentiated in 9 patients (5%). Serosal infiltration was present in 94 patients (50%). In 51 patients (27%) no lymph node metastases were found, while regional lymph node involvement was present in 122 patients (65%), and para-aortic lymph node involvement
Discussion
In the present study, we attempted to evaluate the survival benefit enabled by the resection of extrahepatic disease in patients with liver metastases of colorectal origin by analyzing retrospectively the long-term results after hepatic resection in this patient cohort. We have been using an aggressive approach to colorectal liver metastases with curative intent, and extrahepatic metastases were resected simultaneously with hepatic metastases, whenever a macroscopically curative resection with
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