Original ArticleSmall Cell Lung CancerNivolumab Monotherapy and Nivolumab Plus Ipilimumab in Recurrent Small Cell Lung Cancer: Results From the CheckMate 032 Randomized Cohort
Keywords
Cited by (0)
Disclosure: Dr. Ready has received fees to his institution from Bristol-Myers Squibb during the conduct of the study; has received grants from Merck; and has received personal fees from AbbVie, AstraZeneca, Bristol-Myers Squibb, Celgene, EMD Serono, G1 Therapeutics, Genetech, Merck, Novartis, and Tesaro. Dr. Ott has received grants from ARMO BioSciences, AstraZeneca, Bristol-Myers Squibb, Celldex, CytomX, Genentech, Neon Therapeutics, and Pfizer; and has received personal fees from Alexion, Amgen, Bristol-Myers Squibb, Celldex, CytomX, Genentech, Neon Therapeutics, Novartis, and Pfizer. Dr. Hellmann has received grants from Bristol-Myers Squibb; has received personal fees from AstraZeneca, Bristol-Myers Squibb, Genentech/Roche, Janssen, Merck, Mirati, Nektar, Roche, Shattuck Labs, and Syndax; has received nonfinancial support from AstraZeneca and Bristol-Myers Squibb; and has a patent filed by MSK related to the use of tumor mutation burden to predict response to immunotherapy (PCT/US2015/062208), which has received licensing fees from PGDx. Dr. Zugazagoitia has received personal fees from Guardant Health outside the submitted work. Dr. Hann has received grants and research funds to his institution from AbbVie, Bristol-Myers Squibb, and Merrimack; and has received personal fees from Bristol-Myers Squibb, Genentech/Roche and Ascentage. Dr. de Braud has received personal fees from Amgen, Bristol-Myers Squibb, Daiichi Sankyo, EMD Serono, Ignyta, Incyte, Novartis, Octimet Oncology, Pfizer, Pharm Research Associated, Pierre Fabre, Roche, Servier, and Teofarma. Dr. Antonia has received personal fees from AstraZeneca/MedImmune, Boehringer Ingelheim, Bristol-Myers Squibb, CBMG, Memgen, Merck, and Novartis. Dr. Ascierto has received grants from Array, Bristol-Myers Squibb, and Roche/Genentech; and has received personal fees from 4SC, Array, AstraZeneca, Bristol-Myers Squibb, Genmab, Idera, Immunocore, Incyte, MedImmune, Merck Serono, MSD, NewLink Genetics, Novartis, Pierre Fabre, Roche/Genentech, Sandoz, Sanofi, Sun Pharma, Syndax, and Ultimovacs. Dr. Moreno has received personal fees from Bristol-Myers Squibb. Dr. Atmaca has received travel grants and personal fees from Bristol-Myers Squibb. Dr. Taylor has received grants from BioAtla; and has received personal fees from ArQule, Array BioPharma, Bayer, Blueprint Medicines, Bristol-Myers Squibb, Eisai Inc., Loxo Oncology, and Novartis. Dr. Amin has received personal fees from Array BioPharma, Bristol-Myers Squibb, Dynavax, Exelixis, Merck, Novartis, Pfizer, and Regeneron; and has received nonfinancial support from Bristol-Myers Squibb, Dynavax, and Merck. Dr. Camidge has received personal fees from Bristol-Myers Squibb. Dr. Horn has received research support paid to the institution by Bristol-Myers Squibb; has received personal fees from Abbvie, AstraZeneca, Bristol-Myers Squibb, Genetech-Roche, EMD Serono, Incyte, Merck, and Xcovery; and has received grants from Boehringer Ingelheim, Bristol-Myers Squibb, and Xcovery. Dr. Calvo has received personal fees from Abbvie, Alkerme, Amcure, Astellas, AstraZeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Celgene, Cerulean Pharma, EUSA, GLG, Gehrmann Consulting, Gilead, Guidepoint, Janssen-Cilag, Medscape, Merck, Nanobiotix, Novartis, OncoDNA, Pfizer, Pierre Fabre, PsiOxus Therapeutics, Roche, Seattle Genetics, and Servier; holds leadership roles for INTHEOS, START Madrid, and HM Hospitals Group; stocks/ownership for International Cancer Consultants, Oncoart Associated, and START Madrid; has received research funding from AstraZeneca, Beigene, and Novartis; and has received fees to his institution from Abbvie, ACEO, Amcure, AMGEN, Astellas, AstraZeneca, BeiGene, Boehringen Ingelheim, Boston Therapeutics, Bristol-Myers Squibb, CytomX, Daiichi, DebioPharm, Dynavax, Genentech/Roche, GSK, H3, Incyte, Innovio, Janssen, Kura, Lilly, Loxo, Macrogenics, Menarini, Merck, Mersana, Merus, Millenium, MSD Nanobiotix, Nektar, Novartis, ORCA, Pfizer, PharmaMar, Principia, PsiOxus, PUMA, Regeneron, Rigontec, Sanofi, Seattle Genetics, Spectrum, Synthon, Taiho, Takeda, Tesaro, and Transgene. Dr. Callahan has received grants from Bristol-Myers Squibb; has received personal fees from AstraZeneca/MedImmune, Incyte, Merck, and Moderna; and a family member is employed at Bristol-Myers Squibb. Dr. Spigel has received grants to his institution from Bristol-Myers Squibb, AbbVie, Acerta Pharma, Aeglea Biotherapeutics, Amgen, ARMO Biosciences (Lilly), Astellas Pharma, AstraZeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Celgene, Celldex, Clovis Oncology, Daiichi Sankyo, EMD Serono, Foundation Medicine, G1 Therapeutics, Genentech/Roche, GlaxoSmithKline, GRAIL, Ipsen, Lilly, Millennium, Nektar, Neon Therapeutics, Novartis, Oncogenex, Pfizer, Takeda, Tesaro, Transgene, and University of Texas-Southwestern; and has received fees for his institution from AbbVie, Amgen, AstraZeneca, Boehringer Ingelheim, Celgene, Evelo, Foundation Medicine, Genentech/Roche, GlaxoSmithKline, Illumina, Lilly, Merck, Moderna Therapeutics, Nektar, Novartis, Pfizer, PharmaMar, Precision Oncology, Takeda, and TRM Oncology. The remaining authors declare no conflict of interest.