Short report
A new internet tool to report peritoneal malignancy extent. PeRitOneal MalIgnancy Stage Evaluation (PROMISE) application

https://doi.org/10.1016/j.ejso.2016.03.015Get rights and content

Abstract

Based on the importance of assessing the true extent of peritoneal disease, PeRitOneal MalIgnancy Stage Evaluation (PROMISE) internet application (www.e-promise.org) has been developed to facilitate tabulation and automatically calculate surgically validated peritoneal cancer index (PCI), and other surgically validated scores as Gilly score, simplified peritoneal cancer index (SPCI), Fagotti and Fagotti-modified scores. This application offers computer-assistance to produce simple, quick but precise and standardized pre, intra and postoperative reports of the extent of peritoneal metastases and may help specialized and non-specialized institutions in their current practice but also facilitate research and multicentre studies on peritoneal surface malignancies.

Introduction

The surgical management of peritoneal malignancy (PM) has progressed rapidly over the last 20 years with the development of cytoreductive surgery (CRS) utilizing peritonectomy procedures combined with hyperthermic intraperitoneal chemotherapy (HIPEC). Improved survival has been achieved for appendiceal cancers including pseudomyxoma peritonei, peritoneal mesothelioma and peritoneal metastases from colorectal or gastric cancer. Careful patient selection is required to optimize outcomes. The extent of peritoneal disease remains one of the most important prognostic factors following surgery for peritoneal spread from primary peritoneal, gastrointestinal and ovarian cancers.1, 2 Clinicians and surgeons need effective tools for quantitative and qualitative assessment of patients who are suitable for CRS with HIPEC.

Section snippets

Quantifying extent of peritoneal disease

From the 2006 International Peritoneal Workshop in Milan, the Peritoneal Cancer Index (PCI) has been recognized as the most useful, reliable and reproducible quantitative prognostic tool to assess the distribution of tumour implants throughout the abdomen and pelvis.3 The abdomen and the pelvis are divided by lines into nine regions (regions 0–8). The small bowel is then divided into four regions. Regions 9 and 10 define upper and lower portions of the jejunum, and regions 11 and 12 define the

Presentation

Based on the importance of assessing the true extent of peritoneal disease, we have developed an internet application called PeRitOneal MalIgnancy Stage Evaluation (PROMISE) that automatically calculates PCI and other surgically validated scores as Gilly score, SPCI, Fagotti and Fagotti-modified scores. This application was initially developed on an Excel platform by expert radiological and surgical teams from a tertiary referral centre for CRS and HIPEC. The application was modified in

Conclusion

PROMISE internet application offers computer-assistance to produce simple, quick but precise and standardized pre, intra and postoperative reports of the extent of PM and may help specialized and non-specialized institutions in their current practice but also facilitate research and multicentre studies on peritoneal surface malignancies.

Conflict of interest statement

All authors have no financial conflicts of interest or financial ties to disclose.

Source of funding

The work for this manuscript was not financially supported and none of the authors had any relevant financial relationships.

Ethical approval

Not applicable.

Acknowledgements

The members of the BIG-RENAPE and RENAPE Working Group include:

Julio Abba, MD (Department of Digestive Surgery, Grenoble University Hospital, Grenoble, France); Karine Abboud, MD (Department of General Surgery, CHU Hospital, Jean Monnet University, Saint Étienne, France); Catherine Arvieux, MD, PhD (Department of Digestive Surgery, Grenoble University Hospital, Grenoble, France); Gisèle Balagué, MD (Department of Radiology, Claudius Regaud Institute IUTC, Toulouse, France); Vincent Barrau

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1

Collaborators [BIG-RENAPE (Digestive Peritoneal Carcinomatosis database) – RENAPE (French National Network of Peritoneal Surface Malignancies) Working Groups] are listed at the end of the manuscript (in the Acknowledgements).

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