Cell Systems
Volume 8, Issue 5, 22 May 2019, Pages 412-426.e7
ArticleAdaptation of Human iPSC-Derived Cardiomyocytes to Tyrosine Kinase Inhibitors Reduces Acute Cardiotoxicity via Metabolic Reprogramming
Under a Creative Commons license
open access
Keywords
cardiotoxicity
iPSC-derived cardiomyocytes
tyrosine kinase inhibitor
mitochondrial energetics
drug adaptation
aerobic glycolysis
metabolic reprogramming
transcriptome
proteome
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Present address: Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, 10091 Beijing, China
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© 2019 The Authors. Published by Elsevier Inc.