Biochemical and Biophysical Research Communications
Volume 412, Issue 2, 26 August 2011, Pages 341-346
Epidermal growth factor receptors destined for the nucleus are internalized via a clathrin-dependent pathway
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Highlights
► EGF and its receptor translocates to the nucleus in liver cells. ► Real time imaging shows that EGF moves to the nucleus. ► EGF moves with its receptor to the nucleus. ► Dynamin and clathrin are necessary for EGFR nuclear translocation.
Keywords
Epidermal growth factor receptor
Nuclear translocation
Liver
Clathrin
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These authors contributed equally to this work.
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