Original articleGeneral thoracicEarly Recurrence and Death After Esophagectomy in Patients With Esophageal Squamous Cell Carcinoma
Section snippets
Patient Demographics
Five hundred and thirty-three consecutive patients with thoracic esophageal squamous cell carcinoma underwent esophagectomy in our institution from January 2002 to January 2005. There were 469 men and 64 women, with the age range from 40 to 90 years (median age, 62 years). The diagnosis was established by initial barium esophagogram followed by endoscopic biopsies with documented carcinoma as histologic evidence. The diseases were staged according to the American Joint Committee on Cancer
Results
There were 8 operative deaths (within 30 days after operation), for an operative mortality of 1.5%. The mean number of lymph node resections was 16.4, and the number of positive nodes was 827 of 8,741. The survival and recurrence status could be ascertained in 498 of 533 patients, with a 5-year follow-up rate of 93.4%. There were 440 men and 58 women. The median follow-up of these patients was 35 months (range, 1 to 89 months).
Comment
Because similar treatment often results in a different outcome for patients with esophageal cancer, an individualized therapy for these patients has been of great interest [8]. Accurate prediction of response to a given therapy is the prerequisite of therapy individualization. If patients cannot survive longer than the natural course of esophageal cancer after their operation, the surgical therapy then should not be recommended. Therefore, the understanding of the pattern of death and risk
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