Original articleGeneral thoracicSingle-Stage Surgical Treatment of Synchronous Bilateral Multiple Lung Cancers
Section snippets
Patients and Methods
The Toranomon Hospital Institutional Review Board of Clinical Research approved this study, and the need for informed consent from patients was waved because of its retrospective design. From April 1999 to December 2004, 674 patients underwent surgery for primary lung cancer in our department. A retrospective examination of their clinical records indicated that for 22 patients, preoperative CT revealed bilateral multiple lesions (Table 1).
Single-stage bilateral surgical treatment was applied,
Results
During the study period, 19 of 674 patients were shown to have SBMLC, corresponding to 2.8% of all patients who underwent surgical treatments of primary lung cancers at our hospital. Patient characteristics are listed in Table 1. The patients (6 men, 13 women) were a median age of 65.8 years (range, 52 to 80 years). At the time of operation, 8 (42%) of 19 patients (6 men, 2 women) were smokers, and the remaining 11 patients (58%), who were all women, had no history of smoking. Three patients
Comment
The detection rate of synchronous multiple lung tumors has recently increased owing to advances in diagnostic radiographic techniques and the introduction of helical CT in the screening of lung cancers [1, 2, 3]. Prevalence of multiple primary lung cancers remains unclear and varies in the literature from 0.8% to 10.0% for both synchronous and metachronous cancers [8, 9, 10, 11, 12]. For synchronous multiple cancers alone, prevalence varies from 0.3% to 4.6%. In our study, 3.3% of patients who
References (19)
- et al.
Surgical treatments for multiple primary lung adenocarcinoma of the lung
Ann Thorac Surg
(2004) - et al.
Multiple primary lung cancers
J Thorac Cardiovasc Surg
(1975) - et al.
Second primary lung cancer
Ann Thorac Surg
(1995) - et al.
Long term survivors after resection of lung carcinoma
J Thorac Cardiovasc Surg
(1978) - et al.
Operative approach for multiple primary lung carcinomas
J Thorac Cardiovasc Surg
(1998) - et al.
Major pulmonary resections: pneumonectomies and lobectomies
Ann Thorac Surg
(1993) - et al.
Better pulmonary function and prognosis with video-assisted thoracic surgery than with thoracotomy
Ann Thorac Surg
(2000) - et al.
The results of therapy for bilateral multiple primary lung cancers: 30 years experience in a single centre
Eur J Surg Oncol
(2004) Multiplicitat von Carcinomen bei einem Fall von sog: “Schneeberger” Lungenkrebs mit tuberkulose
Virchows Arch
(1924)
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