Brief reviewCell Biology of Tissue Factor, an Unusual Member of the Cytokine Receptor Family☆
Section snippets
Acknowledgements
The authors are grateful to Dr Tita Ritsema for her critical reading of this manuscript. The authors are supported by the “Nederlandse Hart Stichting” (NHS99.188).
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Cited by (37)
Subcellular localization of tissue factor and human coronary artery smooth muscle cell migration
2012, Journal of Thrombosis and HaemostasisCitation Excerpt :Previous studies reported that cells lacking FLN have impaired locomotion [11,12]. TF, a member of the cytokine receptor family, is a 47‐kDa glycosylated transmembrane protein [13,14] whose activity is modulated by a variety of factors, including its membrane domain association, the phosphatidylserine transmigration to the outer leaflet of the plasma membrane [15,16] and the sphingomyelin levels [10]. TF activity is also modulated by the redox state of its membrane proximal cysteine pair (Cys186/Cys209) [17], as oxidation of this cysteine pair increases the procoagulant activity of TF.
Membrane microvesicles: Macromessengers in cancer disease and progression
2010, Thrombosis ResearchDifferential functions of tissue factor in the trans-activation of cellular signalling pathways
2007, AtherosclerosisCitation Excerpt :In addition to its function as the principal initiator of the extrinsic pathway of coagulation, TF has also been shown to be able to initiate cellular signalling mechanisms leading to alterations in patterns of gene expression [1–8].
Culture medium modulates proinflammatory conditions of human pancreatic islets before transplantation
2006, American Journal of TransplantationCancer-associated thrombosis
2006, Blood Cells, Molecules, and DiseasesA review on pro- and anti-angiogenic factors as targets of clinical intervention
2006, Pharmacological Research
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