Flat neoplastic lesions of the colon and rectum detected by high-resolution video endoscopy and chromoscopy☆,☆☆,★
Section snippets
MATERIALS AND METHODS
From 2373 patients referred for colonoscopy to the section of gastrointestinal endoscopy at the Karolinska Hospital during 1992 and 1993, we selected at random 347 patients for a special study with high-resolution video endoscopy and chromoscopy. One hundred fifteen patients were excluded because of inflammatory bowel disease (n =109), hereditary nonpolyposis colorectal cancer (n = 4), or familial adenomatous polyposis (n = 2). A total of 232 patients were finally included in the study. The
RESULTS
The results are condensed in Fig. 1.
DISCUSSION
In previous studies, we have demonstrated that the colorectal mucosa is almost translucent when observed with conventional endoscopic illumination and it is therefore difficult to visualize minute changes in its epithelial surface.27, 28, 30 In this study, we combined high-resolution video endoscopy and chromoscopy to enhance the surface details of the colorectal mucosa.30 By this method, we detected 109 flat neoplastic polyps in 55 (24) of 232 patients.
With the continuing improvement in the
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Patients With Nonpolypoid (Flat and Depressed) Colorectal Neoplasms at Increased Risk for Advanced Neoplasias, Compared With Patients With Polypoid Neoplasms
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2013, Gastroenterology Clinics of North America
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From the Section of Gastrointestinal Radiology and Endoscopy, Department of Diagnostic Radiology and Pathology, Karolinska Hospital, Stockholm, Sweden.
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Reprint requests: Premysl Slezak, MD PhD, Section of Gastrointestinal Radiologhy and Endoscopy, Deparment of Diagonistic Radiology, Karolinska Hospital, 171 76, Stockholm, Swenden.
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