Brief ObservationsDepression, Palpitations, and Unilateral Pulsatile Tinnitus due to a Dopamine-secreting Glomus Jugulare Tumor
Section snippets
Case Report
A 40-year-old woman was admitted to hospital in 1989 with a 9-month history of pulsation and aching in the left ear, and depression. Her past history was otherwise unremarkable. Her brother had died from a metastatic norepinephrine-secreting pheochromocytoma. Examination showed blood pressure and hearing were normal, and cranial nerves were intact. A computed tomography (CT) scan revealed a tumor in the left jugular canal, deroofing the facial nerve canal and eroding the jugular foramen. A
Discussion
Glomus jugulare tumors arise from paraganglia of the ninth and tenth cranial nerves. They are the most common tumor of the middle ear and can occur sporadically, in which case women are more often affected, or in a heredofamilial pattern favoring men. Derived from the same neural crest tissue as the adrenal medulla, these tumors have the potential to synthesize and secrete catecholamines. Functional activity is thought to occur in only 1% to 3% of cases, however, and norepinephrine is normally
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Cited by (10)
Management of exclusively dopamine-secreting abdominal pheochromocytomas
2013, Journal of the American College of SurgeonsCitation Excerpt :Cases of dopamine-secreting pheochromocytomas were selected if catecholamines (and particularly dopamine) secretion was presented and tumor localization was presented. We found 35 cases of abdominal dopaminomas (from 11 articles5-15; Table 1) and 39 cases of head and neck dopaminomas (from 16 articles13,14,16-29). All of these articles are case reports or small case series.
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