The Journal of Steroid Biochemistry and Molecular Biology
II. Oncogenes and growth factorsThe androgen receptor: Functional structure and expression in transplanted human prostate tumors and prostate tumor cell lines
References (34)
- et al.
Nuclear receptors enhance our understanding of transcription regulation
Trends Genet.
(1988) Gene regulation by steroid hormones
Cell
(1989)- et al.
Cloning, structure and expression of a cDNA encoding the human androgen receptor
Biochem. Biophys. Res. Commun.
(1988) - et al.
The N-terminal domain of the human androgen receptor gene is encoded by one large exon
Mol. Cell. Endocrinol.
(1989) - et al.
Characterization of antibodies against the N-terminal domain of the human androgen receptor
Mol. Cell. Endocrinol.
(1989) - et al.
Molecular cloning and characterization of novel prostate antigen cDNAs
Biochem. Biophys. Res. Commun.
(1988) - et al.
A technique for radiolabeling DNA restriction enVonuclease fragments to high specific activity
Anal. Biochem.
(1983) - et al.
Unusual specificity of the androgen receptor in the human prostate tumor cell line LNCaP: high affinity for progestagenic and estrogenic steroids
Biochim. Biophys. Acta
(1990) The steroid and thyroid hormone receptor superfamily
Science
(1988)- et al.
Steroid receptor family: structure and functions
Endocr. Rev.
(1990)
Molecular cloning of human and rat complementary DNA encoding androgen receptors
Science
Cloning of human androgen receptor complementary DNA and localization of the X chromosome
Science
Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors
The human androgen receptor: complementary deoxyribonucleotide cloning, sequence analysis and gene expression in prostate
Mol. Endocrinol.
Characterization and expression of cDNA encoding the human androgen receptor
The endocrinology and developmental biology of the prostate
Endocr. Rev.
Androgen receptor heterogeneity in human prostatic carcinomas visualized by immunohistochemistry
J. Pathol.
Cited by (59)
Reproductive and nonreproductive actions of testosterone
2018, Encyclopedia of Endocrine DiseasesAttenuation of androgenic regulation by brefeldin A in androgen-responsive prostate cancer cells
2013, Urologic Oncology: Seminars and Original InvestigationsCitation Excerpt :For experiments, LNCaP cells were seeded in 6-well plates or T-75 flasks at 1 × 105 cells/ml, with or without brefeldin A (BFA) (Epicentre Technologies, Madison, WI). In some experiments, cells were cultured in medium with 5% charcoal-stripped FBS (CS-FBS) containing a negligible amount of steroids [12], and DHT (5α-dihydrotestosterone) was also used as an androgenic regulator. Cell number/viability was determined by trypan blue exclusion method.
Progression of prostate cancer: Multiple pathways to androgen independence
2009, Cancer LettersCitation Excerpt :These findings suggest that the variability in AR content increases with the progression of the disease and might in part account for hormone resistance [74–77]. Absence of AR mRNA and protein expression has been shown in the androgen-independent human prostate tumor cell lines DU145 and PC3 [78,79]. The loss of AR expression in these androgen-independent cells appears to occur at the transcriptional level through CpG methylation of the AR promoter and histone deacetylation, instead of at the genomic level through either deletion or mutation [6,80–83].
Divergent biological effects of estradiol and diethylstilbestrol in the prostate cancer cell line MOP
2005, Journal of Steroid Biochemistry and Molecular Biology