Inhibitory effect of Korean mistletoe (Viscum album coloratum) extract on tumour angiogenesis and metastasis of haematogenous and non-haematogenous tumour cells in mice
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Cited by (70)
Three new bioactive flavonoid glycosides from Viscum album
2019, Chinese Journal of Natural MedicinesMistletoe alkaloid fractions alleviates carbon tetrachloride-induced liver fibrosis through inhibition of hepatic stellate cell activation via TGF-β/Smad interference
2014, Journal of EthnopharmacologyCitation Excerpt :Despite therapeutic use of mistletoe for the past several decades, the mechanisms of action of mistletoe are not completely understood. Mistletoe extract has been shown to have antioxidant (Orhan et al., 2005; Yao et al., 2007), anti-angiogenic (Yoon et al., 1995; Park et al., 2001; Van Huyen et al., 2002), and immunomodulatory effects (Tusenius et al., 2005; Elluru et al., 2006; Van Huyen et al., 2006). Our previous studies have demonstrated that mistletoe alkali has a protective effect against carbon tetrachloride (CCl4) toxicity by inhibiting the oxidative damage and stimulating glutathione S-transferas activities (Shi et al., 2006).
Enhanced dendritic cell maturation by the B-chain of Korean mistletoe lectin (KML-B), a novel TLR4 agonist
2014, International ImmunopharmacologyCitation Excerpt :EML exhibits immunomodulatory effects, such as, the enhancement of the phagocytic activities and the release of cytokines by granulocytes and monocytes [14–16]. Korean mistletoe (Viscum album coloratum) extract is also reported to have a variety of biological activities [17–21]. In addition, Korean mistletoe lectin (KML), which is similar to lactin II of EML, shows specificity toward galactose and N-acetyl-galactosamine [22].
Antiangiogenic activity of neutral lipids, glycolipids, and phospholipids fractions of Pinus halepensis Mill. seeds
2014, Industrial Crops and ProductsCitation Excerpt :Most investigations have been made in the past on angiogenesis inhibitors and promoters from plants have been focused mainly on phenolic extracts but very little about the lipid extracts. Genistein (diphenolic isoflavonoids and lignans) (Fotsis et al., 1993), shikonin from Lithospermum erythrorhizon (Hisa et al., 1998), Viscum album coloratum extract (Yoon et al., 1995), ether fraction of water-soluble extract of Populus nigra leaves (Glinkowska et al., 1997), Soybean phytochemicals (Zhou et al., 1999), Chrysobalanus icaco methanol extract (Alves De Paulo et al., 2000), Cassia garrettiana heartwood extract (Kimura et al., 2000), Agaricus blazei extract (Takaku et al., 2001), epigallocatechin gallate from green tea (Jung and Ellis, 2001), resveratrol from grapes (Brakenhielm et al., 2001), beta-sitosterol from Aloe vera (Choi et al., 2002), boiling water extracts of Epimedium sagittatum stem and leaves, Trichosanthes kirilowii fruit walls and Dalbergia odorifera root heartwood showed the strong promoting angiogenesis activity in vivo (Wang et al., 2004). The concentrations (100 μM and 500 μM) of lipid fractions (NL, GL and PL) were used to examine the inhibitory effect on tube formation (Fig. 3).
TLR4-mediated activation of mouse macrophages by Korean mistletoe lectin-C (KML-C)
2010, Biochemical and Biophysical Research CommunicationsCitation Excerpt :The biological and immunomodulatory functions of KML-C have been well documented. KML-C has been shown to have anti-cancer activity [16–18] to augment cytokine induction [19,20], to induce nitric oxide (NO) production from macrophages [21], to activate NK cells resulting in anti-cancer activity [18], and to function as a mucosal adjuvant that protects mice from heterosubtypic influenza virus infections [22]. However, the underlying cellular and molecular mechanisms involved in those functions have yet to be discovered.
Viscum album L. & Abies alba borisii regis effects on platelet aggregation and tumor metastasis
2019, Journal of Applied Pharmaceutical Science