Review letterMicronuclei in exfoliated human cells as a tool for studies in cancer risk and cancer intervention
References (27)
A rapid in vivo test for chromosomal damage
Mutat. Res.
(1973)- et al.
Association of bacteriuria and urinary nitrosamine formation with Schistosoma haematobium infection in the Qalyub area of Egypt
Trans. R. Soc. Trop. Med. Hyg.
(1982) - et al.
Sensitivity comparison of chromosome analysis and micronucleus test in mouse bone marrow
Mutat. Res.
(1980) Significance of the karyorrhectic index in 1,2-dimethylhydrazine carcinogenesis
Cancer Letters
(1979)The micronucleus test
Mutat. Res.
(1975)- et al.
Viruses and mammalian chromosomes. I. Localization of chromosome aberrations after infection with Herpes simplex virus
Virology
(1964) - et al.
Elevated frequency of micronucleated cells in the buccal mucosa of individuals at high risk for oral cancer: betel quid chewers
Cancer Letters
(1982) - et al.
A micronucleus technique for detecting clastogenic effects of mutagens/carcinogens (DEN, DMN) in hepatocytes of rat liver in vivo
Mutat. Res.
(1980) Cytogenetic effects in the mouse of 17 chemical mutagens and carcinogens evaluated by the micronucleus test
Mutat. Res.
(1978)- et al.
A comparison of diameters of micronuclei induced by clastogens and by spindle poisons
Mutat. Res.
(1980)
The mutagenic activity of 61 different agents as determined by micronucleus, Salmonella and sperm abnormality assays
Can. J. Genet. Cytol.
The origin of human cancers
Nature (London)
A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia
Nature (London)
Cited by (148)
Impact of infections, preneoplasia and cancer on micronucleus formation in urothelial and cervical cells: A systematic review
2021, Mutation Research - Reviews in Mutation ResearchCitation Excerpt :One of the first studies with urothelial cells was published by Stich et al. [1] with material from patients with schistosomiasis in 1985. The first trial with cervical cells was realized by the same authors [2] in females with cervical dysplasia (DYS) and cervical cancer (CC) in 1984. In the following years, a number of investigations was realized with exfoliated cells from the bladder (urine derived cells, UDC) which concerned mainly the effects of occupational and life style factors (for review see Nersesyan et al. [3]).
Micronuclei and upper body cancers (head, neck, breast cancers) a systematic review and meta-analysis
2021, Mutation Research - Reviews in Mutation ResearchCitation Excerpt :These studies reported high increases in MN frequency in buccal cells of tobacco/betel quid chewers expecially at the site of contact where the quid or tobacco mixture was kept compared to the opposite site of the mouth [20,21]. Increased frequencies of MN in buccal cells demonstrated also the strong synergistic effect between smoking habit and alcohol consumption in the modulation of chromosome instability [22]. Furthermore the MN assay in buccal cells was applied to investigate the level of chromosomal damage in cancerous and precancerous cells collected directly from the affected tissues [23].
Inorganic arsenic: A non-genotoxic carcinogen
2016, Journal of Environmental Sciences (China)Cytogenetic biomonitoring of occupationally exposed workers to ashes from burning of sugar cane in Ahome, Sinaloa, México
2016, Environmental Toxicology and PharmacologyCitation Excerpt :The samples were placed on a slide, air dried and fixed with methanol–acetic acid (3:1), and were stained with the Feulgen reaction. Genetic abnormalities were evaluated according to the procedure of Stick and Rosin (1984) and Martínez-Valenzuela et al. (2009) by observing 1000 cells per individual, on each slide. They were counted and classified according to Tolbert et al. (1992) and Thomas et al. (2009) to determine the frequency of MN and other nuclear abnormalities such as pyknosis, broken-egg, karyolysis and binucleate cells.
Comparative evaluation of mutagenic effects of two cone-beam computed tomography in oral mucosa cells
2023, Diagnostic CytopathologyArtisanal Gem Mining in Brazil: A Source of Genotoxicity and Exposure to Toxic Elements
2023, International Journal of Environmental Research and Public Health