Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapy
References (317)
- et al.
Hepatic-mediated elevation and maintenance of metastatic tumor cell glutathione
Biochem. Pharmac.
(1986) - et al.
Function of γ-glutamyl transpeptidase
J. biol. Chem.
(1981) Inhibition and enhancement of microsomal drug metabolism by diethyl maleate
Biochem. Pharmac.
(1978)- et al.
Dynamic state of glutathione in blood plasma
J. biol. Chem.
(1980) - et al.
Intracellular delivery of cysteine
Meth. Enzym.
(1987) - et al.
Glutathione monoesters
Analyt. Biochem.
(1989) - et al.
Direct evidence for inter-organ transport of glutathione and that the non-filtration renal mechanism for glutathione utilization involves γ-glutamyl transpeptidase
Biochem. biophys. Res. Commun.
(1980) - et al.
Glutathione monoethyl ester; preparation, uptake by tissues, and conversion to glutathione
Archs. Biochem. Biophys.
(1985) The occurrence of cystinylglycine in blood plasma
Biochim. biophys. Acta
(1979)- et al.
Glutathione depletion sensitizes tumor cells to oxidative cytolysis
J. biol. Chem.
(1982)
Relationship between intracellular glutathione levels and hypoxic cell radiosensitivity
Pharmac. Ther.
(1988)
Alloxan diabetes and the lens
Am. J. Ophthal.
(1950)
Glutathione biosynthesis in the isolated perfused rat lung: Utilization of extracellular glutathione
FEBS Letts.
(1984)
The effect of l-buthionine sulfoximine on the aerobic radiation response of A549 human lung carcinoma cells
Int. J. Radiat. Oncol. Biol. Phys.
(1986)
Quantitative nutritional studies with water-soluble, chemically defined diets. III. Individual amino acids as sources of “non-essential” nitrogen
Archs Biochem. Biophys.
(1957)
The synthesis of glutathione in isolated liver
J. biol. Chem.
(1949)
The oxidation of ascorbic acid and its reduction in vitro and in vivo
J. biol. Chem.
(1937)
γ-Glutamyl amino acids; Transport and conversion to 5-oxoproline in kidney
J. biol. Chem.
(1985)
Buthionine sulfoximine inhibition of cystine uptake and glutathione biosynthesis in human lung carcinoma cells
Toxic. appl. Pharmac.
(1985)
Role of glutathione in the radiation response of mammalian cells in vitro and in vivo
Pharmac. Ther.
(1990)
Tumor sulphydryl levels and sensitivity to the nitrogen mustard merophan
Biochem. Pharmac.
(1963)
Session II: Keynote Address, Thiol-induced biochemical modification of chemo- and radio-responses
Int. J. Radiat. Oncol. biol. Phys.
(1986)
Glutathione reductase of wheat germ
J. biol. Chem.
(1951)
Protection against the toxicity of alkylating agents by thiols: The mechanism of protection and its relevance to cancer chemotherapy. A review
Eur. J. Cancer
(1966)
Enzymatic reactions of methionine sulfoximine, conversion to the corresponding α-imino and α-keto acids, and to α-ketobutyrate and methane sulfinimide
J. biol. Chem.
(1976)
On the chemistry and biochemistry of 3-mercaptopyruvic acid, the α-keto acid analog of cysteine
J. biol. Chem.
(1982)
Effect of diethyl-maleate and other glutathione depletors on protein synthesis
Biochem. Pharmac.
(1986)
An enzyme concerned with the formation of hydroxy acids from ketonic anhydrides
J. biol. Chem.
(1913)
On glyoxalase
J. biol. Chem.
(1913)
Glyoxalase. Part III. The distribution of the enzyme and its relation to the pancreas
J. biol. Chem.
(1913)
3he replacement by thiazolidinecarbozylic acid of exogenous cysteine and cysteine
J. Nutr.
(1958)
Toxic effects of extended glutathione depletion by buthionine sulfoximine on murine mammary carcinoma cells
J. Radiat. Oncol. biol. Phys.
(1986)
Antioxidant and co-antioxidant activity of vitamin C. The effect of vitamin C, either alone or in the presence of vitamin E or a water-soluble vitamin E analogue, upon the peroxidation of aqueous multilamellar phospholipid liposomes
Biochim. biophys. Acta
(1985)
Role of the glutathione-glutathione peroxidase cycle in the cytotoxicity of the anticancer quinones
Pharmac. Ther.
(1990)
The rate of metabolism of brain and liver glutathione in the rat studied with C14-glycine
J. biol. Chem.
(1956)
The effects of buthionine sulphoximine on glutathione depletion and xenobiotic biotransformation
Biochem. Pharmac.
(1984)
Extraction of glutathione by the isolated perfused rabbit kidney
J. surg. Res.
(1976)
Superoxide radical and hydrogen peroxide in mitochondria
Reversal of age-associated decline in immune responsiveness by dietary glutathione supplementation in mice
Mechanisms of Ageing and Development
(1987)
l-Buthionine-SR-sulfoximine: Mechanism of action, resolution of diastereomers and use as a chemotherapeutic agent
Differential inhibition of glutamine and γ-glutamycysteine synthetases by α-alkyl analogs of methionine sulfoximine that induce convulsions
J. biol. Chem.
(1978)
Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)
J. biol. Chem.
(1979)
Intrahepatic transport and utilization of biliary glutathione and its metabolites
Extracellular metabolism of glutathione accounts for its disappearance from the basolateral circulation of the kidney
J. biol. Chem.
(1984)
γ-Glutamyl-glutathione; natural occurrence and enzymology
J. biol. Chem.
(1986)
Elevation of glutathione in phenylalanine mustard-resistant murine L1210 leukemia cells
J. biol. Chem.
(1987)
Pharmacokinetics of intravenously administered glutathione in the rat
J. Pharm. Pharmac.
(1986)
Transport and direct utilization of γ-glutamylcyst(e)ine for glutathione synthesis
Inhibition of γ-glutamyl transpeptidase and glutathionuria produced by γ-glutamyl amino acids
Marked increase of cysteine levels in many regions of brain after administration of 2-oxothiazolidine-4-carboxylate
FASEB J.
(1989)
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