Analysis of platinum in biological materials by flameless atomic absorption spectrophotometry

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Abstract

The application of flameless atomic absorption spectrophotometry to the quantitation of platinum in body fluids and tissues is described. The method was used on samples obtained from humans and beagles treated with the anticancer drug cis-dichlorodiammine platinum. It can be used to detect platinum concentrations in biological tissues and fluids down to ∼30 ppb. The results obtained by this method were compared with those obtained by neutron activation analysis and were found to be lower in all cases.

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    Spontaneous Deposition Radiochemical Separation for Platinum Determination in Biological Materials

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