Abstract
Objective
The purpose of the current study was to evaluate survival of patients diagnosed in California with adenocarcinoma of the pancreas by demographic and tumor-related factors.
Methods
Through the California Cancer Registry (CCR) we identified all California residents diagnosed with invasive pancreatic adenocarcinoma between 1994 and 2000. Demographic, tumor and treatment information was extracted from the CCR, and socioeconomic status (SES) was assigned based on census block group of residence.
Results
A total of 10,612 eligible patients were identified of whom 1674 (15.8%) underwent surgical resection. Patients of lower SES were less likely to undergo resection and somewhat less likely to survive. Median survival was 3.5 months for patients who were not resected and 13.3 months for those who underwent resection. Adjuvant therapy was associated with a decreased risk of death among patients who underwent resection.
Conclusions
This study is the largest population-based study to date to explore survival from pancreatic cancer among all age groups in a racially diverse population. Median survival was shorter than that reported from other series. Race/ethnicity did not have a significant effect on survival. However patients residing in poor neighborhoods were less likely to undergo resection and somewhat less likely to survive this disease.
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Acknowledgement
The collection of cancer incidence data used in this study was supported by the California Department of Health Services as part of the statewide cancer reporting program mandated by California Health and Safety Code Section 103885, the National Cancer Institute’s Surveillance, Epidemiology and End Results Program, and the Centers for Disease Control and Prevention National Program of Cancer Registries. The ideas and opinions expressed herein are those of the author and endorsement by the State of California, Department of Health Services, the National Cancer Institute and the Centers for Disease Control and Prevention is not intended nor should be inferred.
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This research was supported in part by grants from the Centers for Disease Control, National Program of Cancer Registries, Grant U75-CCU910677; and the National Cancer Institute Grants # CA108370, CA59706 to Dr. Holly and the Rombauer Pancreatic Cancer Research Fund.
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Cress, R.D., Yin, D., Clarke, L. et al. Survival Among Patients with Adenocarcinoma of the Pancreas: A Population-based Study (United States). Cancer Causes Control 17, 403–409 (2006). https://doi.org/10.1007/s10552-005-0539-4
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DOI: https://doi.org/10.1007/s10552-005-0539-4