The complex receptor-ECM interaction in glioma cell invasion is discussed focussing upon the role of integrin receptors and matrix-metalloproteinases. Influencing these molecules or their regulation may lead to novel therapeutic approaches in the treatment of malignant glioma.
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Goldbrunner, R., Bernstein, J. & Tonn, JC. Cell-Extracellular Matrix Interaction in Glioma Invasion. Acta Neurochir (Wien) 141, 295–305 (1999). https://doi.org/10.1007/s007010050301
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DOI: https://doi.org/10.1007/s007010050301