Abstract
Purpose
This project’s purpose was to determine the effects of a home-based reflexology intervention on symptom-related use of health services and work-related productivity during the 11-week study.
Methods
A total of 256 patients were randomized to four weekly reflexology sessions (each lasting 30 min, delivered by lay caregivers who received two training sessions by a professional reflexologist) or attention control. The Conventional Health Service and Productivity Costs Form was used to collect information on health service utilization and out-of-pocket expenditure of symptom management. The Health and Work Performance Questionnaire was used to measure workplace performance for patients during the study period. We used weighted and unweighted logistic and linear regression analyses.
Results
Patients in the reflexology group were less likely to have hospital visits compared to the control group in the weighted unadjusted (odds ratio [OR] = 0.49; 95% confidence interval [CI] = [0.25, 0.97]), unweighted adjusted (OR = 0.35; 95% CI = [0.16, 0.75]), and weighted adjusted (OR = 0.30, 95% CI = [0.13, 0.66]) logistic regressions. Compared to attention control, patients in the reflexology group had lower relative absenteeism in the unweighted adjusted (− 0.32; 95% CI = [− 0.60, − 0.03]) linear regressions and less absolute presenteeism (15.42, 95% CI = [0.87, 29.98]) in the weighted unadjusted analysis.
Conclusion
The reflexology intervention delivered by lay caregivers reduced hospital visits and increased workplace productivity in a short-term period, which has potential for cost saving for health care systems and employers.
Trial registration
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References
Di Lascio S, Pagani O (2017) Is it time to address survivorship in advanced breast cancer? A review article. Breast 31:167–172. https://doi.org/10.1016/j.breast.2016.10.022
Luo Z, Bradley CJ, Dahman BA, Gardiner JC (2010) Colon cancer treatment costs for Medicare and dually eligible beneficiaries. Health Care Financ Rev 31:35–50
Siegel RL, Miller KD, Jemal A (2017) Cancer statistics, 2017. CA Cancer J Clin 67:7–30. https://doi.org/10.3322/caac.21387
Ucuzal M, Kanan N (2014) Foot massage: effectiveness on postoperative pain in breast surgery patients. Pain Manag Nurs 15:458–465. https://doi.org/10.1016/j.pmn.2012.03.001
Cleeland CS, Zhao F, Chang VT, Sloan JA, O’Mara AM, Gilman PB, Weiss M, Mendoza TR, Lee JW, Fisch MJ (2013) The symptom burden of cancer: evidence for a core set of cancer-related and treatment-related symptoms from the Eastern Cooperative Oncology Group Symptom Outcomes and Practice Patterns study. Cancer 119:4333–4340. https://doi.org/10.1002/cncr.28376
Given CW, Bradley C, You M, Sikorskii A, Given B (2010) Costs of novel symptom management interventions and their impact on hospitalizations. J Pain Symptom Manag 39:663–672. https://doi.org/10.1016/j.jpainsymman.2009.07.014
Nipp RD, El-Jawahri A, Moran SM et al (2017) The relationship between physical and psychological symptoms and health care utilization in hospitalized patients with advanced cancer. Cancer 123:4720–4727. https://doi.org/10.1002/cncr.30912
Wyatt G, Sikorskii A, Tesnjak I, Frambes D, Holmstrom A, Luo Z, Victorson D, Tamkus D (2017) A randomized clinical trial of caregiver-delivered reflexology for symptom management during breast cancer treatment. J Pain Symptom Manag 54:670–679. https://doi.org/10.1016/j.jpainsymman.2017.07.037
Boon HS, Olatunde F, Zick SM (2007) Trends in complementary/alternative medicine use by breast cancer survivors: comparing survey data from 1998 and 2005. BMC Womens Health 7:4. https://doi.org/10.1186/1472-6874-7-4
Lengacher CA, Bennett MP, Kip KE, Gonzalez L, Jacobsen P, Cox CE (2006) Relief of symptoms, side effects, and psychological distress through use of complementary and alternative medicine in women with breast cancer. Oncol Nurs Forum 33:97–104. https://doi.org/10.1188/06.ONF.97-104
Quattrin R, Zanini A, Buchini S et al (2006) Use of reflexology foot massage to reduce anxiety in hospitalized cancer patients in chemotherapy treatment: methodology and outcomes. J Nurs Manag 14:96–105. https://doi.org/10.1111/j.1365-2934.2006.00557.x
Cronfalk BS, Strang P, Ternestedt B-M (2009) Inner power, physical strength and existential well-being in daily life: relatives’ experiences of receiving soft tissue massage in palliative home care. J Clin Nurs 18:2225–2233. https://doi.org/10.1111/j.1365-2702.2008.02517.x
Wilkinson S, Lockhart K, Gambles M, Storey L (2008) Reflexology for symptom relief in patients with cancer. Cancer Nurs 31:354–360; quiz 361–362. https://doi.org/10.1097/01.NCC.0000305756.58615.81
Sharp DM, Walker MB, Chaturvedi A, Upadhyay S, Hamid A, Walker AA, Bateman JS, Braid F, Ellwood K, Hebblewhite C, Hope T, Lines M, Walker LG (2010) A randomised, controlled trial of the psychological effects of reflexology in early breast cancer. Eur J Cancer 46:312–322. https://doi.org/10.1016/j.ejca.2009.10.006
McVicar AJ, Greenwood CR, Fewell F et al (2007) Evaluation of anxiety, salivary cortisol and melatonin secretion following reflexology treatment: a pilot study in healthy individuals. Complement Ther Clin Pract 13:137–145. https://doi.org/10.1016/j.ctcp.2006.11.001
Stephenson NLN, Dalton JA (2003) Using reflexology for pain management. A review. J Holist Nurs 21:179–191. https://doi.org/10.1177/0898010103021002007
Stephenson NLN, Swanson M, Dalton J, Keefe FJ, Engelke M (2007) Partner-delivered reflexology: effects on cancer pain and anxiety. Oncol Nurs Forum 34:127–132. https://doi.org/10.1188/07.ONF.127-132
Grealish L, Lomasney A, Whiteman B (2000) Foot massage. A nursing intervention to modify the distressing symptoms of pain and nausea in patients hospitalized with cancer. Cancer Nurs 23:237–243
Stephenson NL, Weinrich SP, Tavakoli AS (2000) The effects of foot reflexology on anxiety and pain in patients with breast and lung cancer. Oncol Nurs Forum 27:67–72
Magill L, Berenson S (2008) The conjoint use of music therapy and reflexology with hospitalized advanced stage cancer patients and their families. Palliat Support Care 6:289–296. https://doi.org/10.1017/S1478951508000436
Ernst E (2009) Is reflexology an effective intervention? A systematic review of randomised controlled trials. Med J Aust 191:263–266
Ernst E, Posadzki P, Lee MS (2011) Reflexology: an update of a systematic review of randomised clinical trials. Maturitas 68:116–120. https://doi.org/10.1016/j.maturitas.2010.10.011
Wyatt G, Sikorskii A, Rahbar MH, Victorson D, You M (2012) Health-related quality-of-life outcomes: a reflexology trial with patients with advanced-stage breast cancer. Oncol Nurs Forum 39:568–577. https://doi.org/10.1188/12.ONF.568-577
Wyatt G, Sikorskii A, Siddiqi A, Given CW (2007) Feasibility of a reflexology and guided imagery intervention during chemotherapy: results of a quasi-experimental study. Oncol Nurs Forum 34:635–642. https://doi.org/10.1188/07.ONF.635-642
Maramaldi P, Dungan S, Poorvu NL (2008) Chapter 3; Cancer treatments. J Gerontol Soc Work 50:45–77. https://doi.org/10.1080/01634370802137793
Scott NW, McPherson GC, Ramsay CR, Campbell MK (2002) The method of minimization for allocation to clinical trials. A review. Control Clin Trials 23:662–674
Wyatt G, Sikorskii A, Rahbar MH, Victorson D, Adams L (2010) Intervention fidelity: aspects of complementary and alternative medicine research. Cancer Nurs 33:331–342. https://doi.org/10.1097/NCC.0b013e3181d0b4b7
Kessler RC, Ames M, Hymel PA, Loeppke R, McKenas DK, Richling DE, Stang PE, Ustun TB (2004) Using the World Health Organization Health and Work Performance Questionnaire (HPQ) to evaluate the indirect workplace costs of illness. J Occup Environ Med 46:S23–S37. https://doi.org/10.1097/01.jom.0000126683.75201.c5
Kessler RC, Barber C, Beck A, Berglund P, Cleary PD, McKenas D, Pronk N, Simon G, Stang P, Ustun TB, Wang P (2003) The World Health Organization Health and Work Performance Questionnaire (HPQ). J Occup Environ Med 45:156–174
Bayliss EA, Ellis JL, Steiner JF (2009) Seniors’ self-reported multimorbidity captured biopsychosocial factors not incorporated into two other data-based morbidity measures. J Clin Epidemiol 62:550–557.e1. https://doi.org/10.1016/j.jclinepi.2008.05.002
Cleeland CS, Mendoza TR, Wang XS, Chou C, Harle MT, Morrissey M, Engstrom MC (2000) Assessing symptom distress in cancer patients. Cancer 89:1634–1646. https://doi.org/10.1002/1097-0142(20001001)89:7<1634::AID-CNCR29>3.0.CO;2-V
Cella D, Riley W, Stone A, Rothrock N, Reeve B, Yount S, Amtmann D, Bode R, Buysse D, Choi S, Cook K, Devellis R, DeWalt D, Fries JF, Gershon R, Hahn EA, Lai JS, Pilkonis P, Revicki D, Rose M, Weinfurt K, Hays R, PROMIS Cooperative Group (2010) The patient-reported outcomes measurement information system (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005-2008. J Clin Epidemiol 63:1179–1194. https://doi.org/10.1016/j.jclinepi.2010.04.011
Driban JB, Morgan N, Price LL, Cook KF, Wang C (2015) Patient-Reported Outcomes Measurement Information System (PROMIS) instruments among individuals with symptomatic knee osteoarthritis: a cross-sectional study of floor/ceiling effects and construct validity. BMC Musculoskelet Disord 16(253):253. https://doi.org/10.1186/s12891-015-0715-y
Ferrans CE (1990) Development of a quality of life index for patients with cancer. Oncol Nurs Forum 17:15–19 discussion 20
Robins JM, Finkelstein DM (2000) Correcting for noncompliance and dependent censoring in an AIDS clinical trial with inverse probability of censoring weighted (IPCW) log-rank tests. Biometrics 56:779–788
Wong A, Azhar A, Cerana MA, Balankari VR, Adabala M, Liu DD, Williams JL, Bruera E (2016) Characteristics of patients with unscheduled versus scheduled visits to outpatient supportive care center (SCC) at a comprehensive cancer center. JCO 34:144–144. https://doi.org/10.1200/jco.2016.34.26_suppl.144
Herman PM, Poindexter BL, Witt CM, Eisenberg DM (2012) Are complementary therapies and integrative care cost-effective? A systematic review of economic evaluations. BMJ Open 2:e001046. https://doi.org/10.1136/bmjopen-2012-001046
Drummond MF, Sculpher MJ, Torrance GW et al (2005) Methods for the economic evaluation of health care programmes, 3rd edn. Oxford University Press, Oxford
Williams F, Jeanetta SC (2016) Lived experiences of breast cancer survivors after diagnosis, treatment and beyond: qualitative study. Health Expect 19:631–642. https://doi.org/10.1111/hex.12372
Ekwueme DU, Trogdon JG, Khavjou OA, Guy GP (2016) Productivity costs associated with breast cancer among survivors aged 18-44 years. Am J Prev Med 50:286–294. https://doi.org/10.1016/j.amepre.2015.10.006
McCarney R, Warner J, Iliffe S, van Haselen R, Griffin M, Fisher P (2007) The Hawthorne Effect: a randomised, controlled trial. BMC Med Res Methodol 7:30. https://doi.org/10.1186/1471-2288-7-30
Acknowledgements
The research team would like to thank our dedicated participants who made this study possible.
Funding
This study was funded by the National Cancer Institute (1 R01CA157459), Principal Investigator: G. Wyatt.
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Luo, Z., Wang, L., Sikorskii, A. et al. Healthcare service utilization and work-related productivity in reflexology intervention for advanced breast cancer women. Support Care Cancer 27, 2837–2847 (2019). https://doi.org/10.1007/s00520-018-4592-4
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DOI: https://doi.org/10.1007/s00520-018-4592-4