Abstract
Background
Laparoscopy-assisted surgery with extraperigastric lymph node dissection for gastric cancers has been described, but the clinical benefits of these surgeries still are unclear. Short-term clinical outcomes were compared between laparoscopy-assisted distal gastrectomy (LADG) and conventional open distal gastrectomy (ODG) for early gastric cancer in a prospective randomized fashion.
Methods
For this study, 28 patients with early gastric cancers in the lower half of the stomach were randomly assigned to either LADG (n = 4) or ODG (n = 14). Postoperative pain, levels of acute inflammatory responses, and pathologic evaluation of the operative specimens were compared.
Results
The LADG group required a significantly shorter period of postoperative epidural anesthesia, showed significantly lower levels of serum interleukin-6 and C-reactive protein, and had no major postsurgery complications. Pathologic examinations showed that surgery was equally radical in the two groups.
Conclusion
The findings show that LADG with extraperigastric lymph node dissection is a safe and less invasive alternative to the open procedure.
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This work was supported in part by the 21st Century COE (Center of Excellence) Programs Grant and a Grant-in-Aid for Scientific Research (#15591377) from the Ministry of Education, Culture, Sports, Science and Technology of Japan.
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Hayashi, H., Ochiai, T., Shimada, H. et al. Prospective randomized study of open versus laparoscopy-assisted distal gastrectomy with extraperigastric lymph node dissection for early gastric cancer. Surg Endosc 19, 1172–1176 (2005). https://doi.org/10.1007/s00464-004-8207-4
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DOI: https://doi.org/10.1007/s00464-004-8207-4