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MR-guided liver tumor ablation employing open high-field 1.0T MRI for image-guided brachytherapy

  • Interventional
  • Published:
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Abstract

Objective

To determine the feasibility and safety of image-guided brachytherapy employing a modified open high-field MR system.

Methods

This is a follow-up study of a development project enabling technologies for interventional use of 1.0T open MRI. Modifications included coils and in-bore visualization, fluoroscopic sequences and user interfaces. We recruited 104 patients with 224 liver malignancies to receive MR-guided brachytherapy. Interventions were performed >20 min after Gd-EOB-DTPA. We recorded interventional parameters including the intervention time (from acquisition of the first scout until the final sequence for brachytherapy treatment planning). Two reviewers assessed MR-fluoroscopic images in comparison to plain CT as used in CT intervention, applying a rating scale of 1–10. Statistical analysis included Friedman and Kendall’s W tests.

Results

We employed freehand puncture with interactive dynamic imaging for navigation. Technical success rate was 218 complete ablations in 224 tumours (97%). The median intervention time was 61 min. We recorded no adverse events related to the use of MRI. No major complications occurred. The rate of minor complications was 4%. Local control at 3 months was 96%. Superiority of MR-fluoroscopic, Gd-EOB-DTPA-enhanced images over plain CT was highly significant (P < 0.001).

Conclusion

MR-guided brachytherapy employing open high-field MRI is feasible and safe.

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Author information

Authors and Affiliations

  1. Klinik für Radiologie und Nuklearmedizin, Universitätsklinikum Magdeburg AöR, Leipzigerstrasse 44, 39120, Magdeburg, Germany

    Jens Ricke, Markus Thormann, Matthias Ludewig, Kerstin Jungnickel, Oliver Grosser, Christian Wybranski & Frank Fischbach

  2. Klinik für Strahlentherapie, Universitätsklinikum Magdeburg AöR, Magdeburg, Germany

    Nils Peters & Peter Hass

  3. Philips Healthcare, Hamburg, Germany

    Jürgen Bunke

Authors
  1. Jens Ricke
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  2. Markus Thormann
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  3. Matthias Ludewig
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  4. Kerstin Jungnickel
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  10. Frank Fischbach
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Correspondence to Jens Ricke.

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Ricke, J., Thormann, M., Ludewig, M. et al. MR-guided liver tumor ablation employing open high-field 1.0T MRI for image-guided brachytherapy. Eur Radiol 20, 1985–1993 (2010). https://doi.org/10.1007/s00330-010-1751-5

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  • DOI: https://doi.org/10.1007/s00330-010-1751-5

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